Chapter 64 :: Morphea and Lichen Sclerosus

Question 1

Circumscribed and generalized Morphea predominate in

Answer 1

Adults

Question 2

present as an atrophic linear plaque on the forehead extending to the scalp (where cicatricial alopecia occurs), brow, nose, and lip

Answer 2

En coup de sabre (“cut of the sword”)

Question 3

characterized by acral sclerosis/sclerodactyly, nail-fold capillary changes, Raynaud phenomenon, characteristic internal organ involvement (eg, pulmonary, renal, and GI), and hallmark autoantibodies

Answer 3

Systemic sclerosis

Question 4

considered a first-line systemic treatment for morphea, especially for deep morphea and rapidly progressive or disabling morphea

Answer 4

Methotrexate

Question 5

presents with porcelain-white atrophic papules coalescing into plaques on the labia minora and majora

Answer 5

Vulvar Lichen Sclerosus

Question 6

Vulvar lichen planus more commonly involves the vagina, whereas LS spares the vagina

Question 7

first-line treatment for genital LS based on randomized controlled trials (RCTs

Answer 7

Ultrapotent topical corticosteroids, most commonly clobetasol propionate 0.05%