Chapter 158 :: Actinomycosis, Nocardiosis, and Actinomycetoma Flashcards
Most common agent of the ACTINOMYCOSIS
Actinomyces israelii
Most common agent of NOCARDIOSIS
Sporotrichoid, cellulitis, abscesses
Extremities (upper > lower)
Nocardia brasiliensis
Nocardia asteroides
Most common agent of the ACTINOMYCETOMA
Nocardia brasiliensis
Actinomadura madurae
Actinomadura pelletieri
Streptomyces somaliensis
Most common agent of the BOTRYOMYCOSIS
Staphylococcus aureus
Escherichia coli
Pseudomonas aeruginosa
treatment of actinomycosis
penicillin G, 18 to 24 million units IV for 2 to 6 weeks, followed by oral penicillin or amoxicillin, to be given for 6 to 12 months
treatment of choice in actinomycetoma
diaminodiphenylsulfone (Dapsone) 100 to 200 mg/day (3 to 5 mg/kg) plus TMP-SMX 160/800 mg twice a day for several months in initial cases; the treatment should continue for up to 2 years