Chapter 10 :: The Immunological Structure of the Skin Flashcards
1
Q
Dual role of the skin
A
Skin barrier function
2
Q
Characterized by (a) its rapid onset, (b) its capacity to discriminate between danger and nondanger only, (c) its lack of memory
A
Innate component
3
Q
Resident cells (nonleukocytic)
A
Keratinocytes*
Fibroblasts
Sebocytes*
Endothelial cells
Nerve cells
4
Q
Play a major role in antiviral defense by the massive production of type I interferons (IFN-α, IFN-β) upon activation of TLR7 and TLR9
A
pDCs
5
Q
The artificial TLR7 ligand imiquimod provides a strong activation signal for pDC
A
6
Q
The largest, and probably the most important, lymphocyte population within NHS
A
T lymphocytes
7
Q
T-Cell Pattern: Psoriasis
A
Th17
