Chapter 3 Lecture - Cellular Form and Function Flashcards
True or false: All organisms are composed of cells
True
____ are responsible for all structural and functional properties of a living organism
Cells
Understanding cells is the key to understanding what three things?
Workings of human body
Mechanisms of disease
Rationale of therapy
What are the 5 components of cell theory?
1) All organisms composed of cells and cell products
2) Cell is the simplest structural and functional unit of life
3) An organism’s structure and functions are due to activities of cells
4) Cells come only from preexisting cells
5) Cells of all species exhibit biochemical similarities
How many types of cells are there in the human body?
About 200 different types
What does the plasma (cell) membrane do and what is it made up of?
It surrounds cell and defines boundaries. Made of proteins and lipids
What 4 things are included in the cytoplasm?
1) Organelles
2) Cytoskeleton
3) Inclusions (stored or foreign particles)
4) Cytosol (intracellular fluid, ICF)
True or false: extracellular fluid (ECF) is one of the basic components of a cell
True
Define organelle
Internal structures of a cell that carry out specialized metabolic tasks
What’s the difference between cytoplasm and cytosol?
Cytoplasm contains the organelles; cytosol does not.
How is the plasma membrane arranged?
In a bilayer
What is the border of the cell?
The plasma membrane
Name 3 functions of the plasma membrane
1) Defines cell boundaries
2) Governs interactions with other cells
3) Controls passage of materials in and out of cell
__% of membrane molecules are lipids
98%
What are the 3 most abundant membrane lipids?
Phospholipids (75% of membrane lipids), cholesterol (20%), and glycolipids (5%)
What does the membrane lipid cholesterol do?
Holds phospholipids still and can stiffen the membrane
What are glycolipids?
Phospholipids with short carbohydrate chains on extracellular face. A type of membrane lipid.
Membrane proteins make up __% of the molecules but __% of the weight of membrane
2% of the molecules but 50% of the weight of membrane
What are the two basic types of membrane proteins, and where are they located?
Integral proteins—penetrate membrane
Peripheral proteins – on the surface of membrane
What is one type of integral protein?
Transmembrane proteins
________ proteins contain both hydrophilic and hydrophobic regions
Transmembrane
Where are transmembrane proteins located?
Some drift in membrane; others are anchored to cytoskeleton
Describe peripheral proteins
- Adhere to one face of the membrane (do not penetrate it)
- Usually tied to the cytoskeleton and an integral protein.
What are some examples of the functions of membrane proteins?
Receptors, enzymes, channels, carriers, cell-identity markers, cell-adhesion molecules, etc
What is the glycoalyx? What is it made up of?
It’s a fuzzy coat external to plasma membrane, and made up of glycoproteins and glycolipids
_______ is unique in everyone but identical twins
Glycocalyx
What does the glycocalyx do?
It helps with protection, immunity to infection, defense against cancer, transplant compatibility, cell adhesion, fertilization, and embryonic development
True or false: Some channel proteins are always open, but others are gated
True
What are channel proteins needed for?
They’re crucial to nerve and muscle function
What are 3 different types of channel proteins?
Ligand-gated channels, voltage gated channels, and mechanically-gated channels
Ligand-gated channels respond to _____
chemical messengers
Voltage-gated channels respond to ____
charge changes
Mechanically-gated channels respond to ____
physical stress on the cell
What is an example of a stretch receptor?
Mechanically-gated channels
Give an example of chemical messengers for ligand-gated channels
Neurotransmitters
Microvilli are best developed in cells specialized in _____
absorption
What are microvilli?
Extensions of the membrane that gives 15 to 40 times more surface area
How big are microvilli?
1-2μm
What is it called when microvilli are very dense and appear as a fringe?
Brush border
What are cilia?
Hair-like processes that are 7–10 μm long
What is one type of cilia?
Motile cilia
____ cilia are found in the respiratory tract, uterine tubes, ventricles of brain, ducts of testes
Motile cilia
What do cilia do?
Beat in waves sweeping material across a surface in one direction
True or false: the flagellum of sperm is the only functioning flagella in humans
True
Describe the structure and movement of flagella
They have a whip-like structure and are much longer than cilium.
Their movement is undulating, snake-like, corkscrew; no power stroke and recovery strokes
What are pseudopods?
Continually changing extensions of the cell that vary in shape and size
What can pseudopods do?
They can be used for cellular locomotion or capturing foreign particles
The plasma membrane is selectively permeable. What does this mean?
It allows some things through, but prevents others from passing