Chapter 28 - The Reproductive Systems Flashcards
What is Scrotum?
A sac of loose skin underlying subcutaneous tissue that contains the Testes
Internally, it is separated into 2 compartments by the Dartos Muscle and a Subcutaneous Layer
What is Testes?
Paired, oval glands in the Scrotum partially covered by the Tunica Vaginalis
Internal to Tunica Vaginalis is a connective tissue capsule, the Tunica Albuginea that extends inwards to form Septa that create compartments
Seminiferous Tubules carry sperm produced within them (Spermatogenesis) out of the Testes
What is Spermatogenesis?
Begins with Spermatogonia:
Diploid Stem Cells that differentiate into Diploid Primary Spermatocytes
Spermatogenic Cells:
1- Spermatogonium (2n) (stem cell):
Undergo Mitosis, some remain as Stem Cells (2n), others pushed away from Basement Membrane and differentiate into Primary Spermatocyte (2n)
2- Primary Spermatocyte (2n):
Undergoes Meiosis I to become 2 Secondary Spermatocytes (n)
3- Secondary Spermatocyte (n):
Undergoes Meiosis II to become 4 Spermatids (n)
4- Spermatid (n):
Undergoes Spermiogenesis and becomes 4 Spermatozoa (n)
5- Sperm Cell or Spermatozoon (n)
What is Sperm?
Designed to reach and penetrate the Secondary Oocyte in order to achieve fertilization and create a Zygote
1- Head:
Consists of a Nucleus with 23 Chromosomes
2- Acrosome:
Covers Head and contains enzymes to help with penetration
3- Neck:
Contains Centrioles that form the Microtubules that make up the rest of the Tail
4- Middle Piece:
Contain Mitochondria that make ATP for locomotion of the Sperm
5- Principal Piece and End Piece:
Make up the Tail used for movement
What are Hormones that Control Testicular Function?
At puberty:
Gonadotropin Releasing Hormone (GnRH):
Stimulate cells in Anterior Pituitary Gland to produce:
1- Luteinizing Hormone (LH):
Stimulates cells in Testes to produce Testosterone
2- Follicle-Stimulating Hormone (FSH):
Stimulates Spermatogenesis
What is Testosterone and Dihydrotestosterone?
Produce several Effects:
1- Prenatal Development
2- Development of Male Sexual Characteristics
3- Development of sexual function
4- Stimulation of Anabolism
Negative Feedback Loop controls blood level of Testosterone
What is Negative Feedback Loop for Increased Blood Testosterone?
1- Increased blood level of Testosterone
2- Cells in Hypothalamus that secrete GnRH decrease GnRH in portal blood
3- Anterior Pituitary Gonadotrophs decrease LH in systemic blood
4- Interstitial Cells in Testes (Leydig Cells) secrete less Testosterone
5- Decrease blood level of Testosterone
What is The System of Ducts in Male Reproductive System?
1- Sperm and fluid travel from the:
Seminiferous Tubules
To Straight Tubules
Then to a network of Ducts, The Rete Testis
2- Efferent Ducts carry the sperm to the Epididymis:
Sperm mature in the Epididymis
Degenerated sperm are reabsorbed
Epididymis propels sperm into the Ductus Deferens (Vas Deferens)
3- Vas Deferens:
Exits the Tail of the Epididymis
Ascends through Spermatic Cord into Pelvis
Loops over the Ureter
Passes over the side and down the posterior surface of the Urinary Bladder
What is Spermatic Cord?
Spermatic Cord:
1- Ascends out of the Scrotum
2- Contains Vas Deferens, Testicular Artery, Veins draining the Testes, Autonomic Nerves, Lymphatic vessels, and the Cremaster muscle
3- Spermatic Cord and Ilioinguinal Nerve pass through the Inguinal Canal which originates at the Deep Inguinal Ring and ends at the Superficial Inguinal Ring
What is Ejaculatory Duct?
Ejaculatory Duct:
Arises from the junction of the Duct from the Seminal Vesicle and the Ampulla of the Vas Deferens
What is Urethra in Males?
Urethra:
Duct shared by Reproductive and Urinary Systems
Both semen and urine pass through the Urethra
1- Prostatic Urethra:
Urethra passes through the Prostate Gland
2- Intermediate Urethra (Membranous Urethra):
Passes through Deep muscles of the Perineum
Surrounded by Bulbourethral Glands (Cowper’s Gland)
3- Spongy Urethra:
Passes through the penis till the External Urethral Orifice
What are the Accessory Glands of the Male Reproductive System?
1- Seminal Vesicles (Glands)
2- Prostate Gland
3- Bulbourethral Gland (Cowper’s Gland)
What is Seminal Vesicles (Glands)?
Secrete an Alkaline, viscous fluid containing:
Fructose
Prostaglandins
Clotting Proteins
What is Prostate?
Single, donut-shaped Gland
Secretes milky acidic fluid containing:
Citric Acid
Proteolytic enzymes
Acid Phosphatase
Seminalplasmin
What is Bulbourethral Gland (Cowper’s Gland)?
Secrete alkaline fluid during sexual arousal that neutralizes acids from urine
And mucus for lubrication
What is Semen?
Mixture of Sperm and Seminal Fluids
Volume of an average ejaculation: 2.5 - 5mL with 50 - 150M sperm/mL
pH: 7.2 - 7.7
What is Penis?
Contains Urethra
Is a passageway for semen and urine
Composed of 3 Cylindrical Masses:
1- Corpus Spongiosum
2- Two Corpora Cavernosa
3- Glans:
Head of penis covered by Prepuce (foreskin)
What is an Erection?
Erection:
Brought by Parasympathetic Innervation leading to Vasodilation of Arterioles in Erectile Tissue
1- Large amounts of blood enter the tissue into dilated blood sinuses
2- Ejaculation is the powerful release of semen due to Sympathetic stimulation
3- Bulbospongiosus, Ischiocavernosus, and Superficial Transverse Perineal muscles contract to force the semen out
What is Mechanisms of Male Erection?
Mechanism:
1- Sight, thoughts, smells, sounds send nerve impulses to Hypothalamus and Limbic System
2- Stimulation of Mechanoreceptors in penis send sensory neuron nerve impulse to Brain and Sacral Spinal Cord
3- Hypothalamus and Limbic System send Descending inputs from brain to Sacral Spinal Cord
4- Nerve impulses sent to Interneuron in Sacral Spinal Cord
5- Nerve impulses sent to Parasympathetic Preganglionic Neuron then Autonomic Ganglion, then Parasympathetic Postganglionic Neuron, all to the erectile tissue of penis
6- Penile arterioles dilate, and penile veins compressed
7- Penis becomes erect
What is Ovaries?
Ovaries:
Paired Glands homologous to Testes
Produce Gametes (mature into Ova)
They are supported by the :
Broad Ligament
Ovarian Ligament
Suspensory Ligament
Produce Hormones:
Progesterone
Estrogens
Inhibin
Relaxin
What is Histology of Ovaries?
Ovaries consist of:
1- Germinal Epithelium:
Covers surface of the Ovary
2- Tunica Albuginea:
Capsule of dense irregular connective tissue
Below the Germinal Epithelium
3- Ovarian Cortex:
Below the Tunica Albuginea
Consists of Ovarian Follicles and Stromal Cells
4- Ovarian Medulla:
Connective tissue
Blood vessels
Lymphatic vessels
Nerves
What is Ovarian Follicles?
Ovarian Follicles:
Contain Oocytes in various stages of development
Follicular Cells
Granulosa Cells
Mature Follicle (Graafian Follicle):
Ready to rupture and expel the Secondary Oocyte
Corpus Luteum:
Develops after ovulation when the empty follicle produces Progesterone, Estrogens, Inhibin, and Relaxin
Stages:
1- Primordial Follicle
2- Primary Follicle
3- Secondary Follicle
4- Mature (Graafian) Follicle:
Contains Follicular fluid
5- Corpus Hemorrhagicum:
Ruptured follicle
Discharge Secondary Oocyte (ovulation) surrounded by Corona Radiata
6- Corpus Luteum:
With blood clot at center
7- Degenerating Corpus Luteum
8- Corpus Albicans