Chapter 23 - Microbial Diseases Of Cardiovascular System Flashcards
Septicaemia is caused by
S.progenies and staph, pseudomonas
Septicaemia symptoms
Fever, chills, laboured breathing, anxiety, lymphangitis
Lymphangitis
Inflamed lymph vessel through arm or leg
Septicaemia risks, causes
Can become sepsis or septic shock
-from wound, UTI or e-coli
Puerperal sepsis
Childbirth fever from s.phosgene’s, transmitted to mother via physicians, nurse or attending
-progresses from uterine tissues to abdominal region
-used to be a common cause of death
Rheumatic fever
Inflammation of heart valve
-mitral valve
-forms vegetation, destroying the hart valve
Rheumatic fever risks and symptoms
-equal to strep throat (GAS)
-period of arthritis, fever, chest pain
Anthrax is caused by
Bacillus anthracis
Bacillus anthracis
-rod
-facilitated aerobic or obligate aerobe
-produce endospore with no lollypop shape
-found in soil and used as bio weapon
Anthrax was discovered by
Robert Koch
-the disease of animals, in GI form
-by burning carcasses
GI form of anthrax
Undercooked food, nausea, hemorrhages in GI—> septicemia
50% death
Cutaneous form of anthrax
Enter through minor cuts
-cause crust lesions called eschar
-septicemia 20% death
Pulmonary form of anthrax
Inhaled endoscope germination, chest pain, breathing difficulty
-septicemia 100% death
-survivors are disabled
Treatment and vaccine for anthrax
-ciprofloaxein, penicillin, erythromycin
-vaccine: six doses in 18 months
Anthrax produces three exotoxins
- Protective toxin—> binds, entry
- Lethal toxin—> phagocytic death
- Edema toxin—> swelling
Gangrene is caused by
Clostridium perifringes
-gas gangrene
Gangrene
Necrotic tissue from cut off blood supply
Gangrene susceptible and travel
Diabetic, abortions or gunshot wounds
Endospore, germination, deep cleaning can reduce spores
Symptoms and toxin of gangrene
Symptoms: abrupt pain, swelling, ooze blood tainted fluid from ruptured vessels, blackening of tissue
Toxin: X toxin, attacks blood vessels, RBC and WBC, lecithin of cell membrane
Why does swelling take place due to gangrene
Swelling from gas production H+ and CO2
-snap, crackle, pop noises and foul orders
Spotted fever is caused by
Ricksetti ricksetti
Spotted fever
-risk, differs form measles, symptoms
-makes its way to heart and destroys valves
-differs from measles as there is a rash on white parts of our bodies (soles of feet, hands)
-cause fever, rash (on white parts)
HHSV-4 or Epstein BARR virus causes
BURKITTS LYMPHOMA
BURKITTS lymphoma
-tug a war on lymphocytes
-fast growing tumour on jaw
Latency of BURKITTS
Not latent in herpes virus, latent in B lymphocytes
BURKITTS productive infection vs nonproductive
P- not latent
N- latent
Infectious mononucleosis
Spread through saliva
-B lymphocytes are non productive
Symptoms of infectious mononucleosis
-starts with fever sore throat, pus, EB in saliva for 18 months, 1.8 million college students fatigue
Nasopharyngeal carcinoma
Cancer of nose and throat
-b lymphocytes
Chronic fatigue syndrome
Yuppie flu
-extreme muscle fatigue
-memory loss
-swollen lymph nodes
-rare death in ruptured spleen
HHSV-5 or CMV (cytomegalovirus)
Retina degeneration, chronic in HIV pt
-sexually transmitted through blood and saliva
T cells in CMV
Infected cells swell and have inclusions
-latent in T cells
-causes Owl’s eyes
CMV when transmitted across placenta
Causes mental retardatiion
Treatment for CMV
Ganciclovir
Malaria is caused by
Protozoa
-plasmodium vivax
Two hosts of malaria
Definitive - mosquitos
Intermediate- human
Malaria causes
Fever, vomiting, severe headaches, pain in muscles
Fever phase of malaria
-paroxyme cycle
Cold phase, hot phase, wet phase (drenched)
Life cycle of malaria: mosquito bite—>
Sporozoite form—> though CV system to liver—> releases mature asexual merozoities in blood
Life cycle of malaria: merozoites in blood
Attack RBC—> form ring stage, which will produce more merozoites—>cycle continues
Life cycle of malaria: cycle continues
RBC dies and releases merozoites —> merozoites can become m/F gametes which cannot mature (wont spread at this point)
Life cycle of malaria: m/F gametes created
Mosque bites—> zygote formation —> new sporozoites
Malaria symptoms, smear, treatment
-enlarged spleen and liver, severe anemia
-need blood smear
-quinine drug