Chapter 21 - Microbial Diseases Of The Skin And Eyes Flashcards
Staphylococcus skin infections can be treated with
Penicillin
Staphylococcus aureus
-folliculis that infect hair follicle
-direct invasion
Sty
S. Aureus
-folliculitis of an eyelash
Furnace
S. Aureus
-pus formation
-red, swollen, pain, pus
Carbuncle
S. Aureus
-inflammation of tissue under skin
-pus, systemic; various organs
-surgical removal or drainage of pus, then start antibiotics
Staphylococcus scalded skin syndrome (SSSS)
-found in children and elderly
-general redness on skin, irritation, rash
-no pus (blisters are filled with clear fluid)
-blisters break and skin peels off in sheets
-leaves skin vulnerable (to something like strep)
Why does SSSS cause blisters
Exfoliative exotoxin that destroys skin cells by breaking ester bonds
-desquamation
treatment for SSSS
Penicillin, isolation
What causes Toxic Shock Syndrome
S. Aureus
-tampons, after child birth and surgery
Symptoms of Toxic Shock Syndrome
Fever, headache, muscle aches, confusion sunburn rash (becomes SSSS), nausea, bloodshot eyes, vomiting, diarrhea, kidney failure, shock, death
Toxic Shock Syndrome (3)
- Super antigenic response due to TSS exotoxins (TSS toxin-1 or TSST-2)
2.tampon nutrient rich breeding ground for exotoxins and entry point
- Tampon material scrapes vagina epithelium (depletes Mg and triggers exotoxins)
Preventative for Toxic Shock Syndrome
Handwashing before and after, absorbency levels, change, do not wear at night
Impetigo symptoms (S. aureus)
Yellowish crusting pus sores, local inflammation
Impetigo (S. aureus)
-no exotoxin
-pyoderma
-affects newborns
-need stain
Streptococcal Pyogenes
Direct invasion -> M proteins
Impetigo (S.pyrogenes)
Yellowish crusting pus sores, no exotoxin, pyoderma, inflammation that enters lymph
-need stain
-affects preschool (3 to 5)
Erysipeias
S. Pyogenes
-infection of dermal regions (deeper)
-reddish
Erysipeias symptoms
Reddish, raised, can become septicaemia
Septicaemia
Blood born
Pyoderma
Enters lymph node and blood stream
Erysipeias is treated with
Penicillin and cephalosporin
Necrotizing fasciitis
S. Pyogenes
-enters via breaks in skin and secretes: collagenaise, hyaluronidase, exotoxin A
-spreads to several organs
-50% mortality rate
Necrotizing fasciitis secretes (3)
-collagenaise
-hyaluronidase
-exotoxin A
-collagenaise
Breaks down tissues
-hyaluronidase
Fragment and breakdown tissue
-exotoxin A
Active
-cells react and disrupt (kill)
Treatment for necrotizing fasciitis
Amputation
Pseudomonas aeruginosa
Gram neg, pyocyanin
pyocyanin
Blue and green pus
Dermatitis
P. Aeruginosa
-goes away by itself, can last 2 weeks
-caused by water
Symptoms of dermatitis
Skin rash