Chapter 2 (page 14) Flashcards
What is cell mediated immunity?
When lymphocytes themselves defend the body. Here the protective factor is living cells.Lymphocytes (T-cells) act against targets (infected tissue, cancer cells, cells of foreign agents) either directly lysing foreign cells or indirectly by releasing chemical mediators that enhance the inflammatory response or activate other lymphocytes or macrophages.
What stage in Development of T-cells, Stem cells leave bone marrow before or shortly after birth and migrate to the ________ where
they undergo their first stage of development.
First stage
Thymus
Newly formed _______ enter blood and move to lymph nodes, liver and spleen. They also have a __________ that is antigen specific “the lock and key mechanism”.
T-cells
plasma membrane
When does the second stage of development of T- cells begins?
development begins when T-cells encounters a macrophage cell that has ingested an antigen. The macrophage must present the ingested antigen to the T-cell in order for the T-cell to recognize the antigen.
Is it true that the T-cell must recognize the ingested antigen that has been presented on the surface of the macrophage and also recognize the macrophage cell.
TRUE
Sensitized T-cells produce clones, which produce ________________ (resistance to disease organisms resulting from the actions of cells).
cell-mediated immunity
What are the types of T-cell?
Helper T-cells
Killer T-cells
Suppressor T-cells
What is the function of killer T-cells?
Can directly attack and kill other cells. They can attack virus infected cells, bacteria infected cells, parasites, cancer cells, etc.
These are regulatory cells that play a central role in the immune response. They stimulate proliferation of other T-cells and B-cells that have already become bound to antigens:
Helper T-cells
These are regulatory cells. They are vital for winding down the immune
response.
Suppressor T-cells
What is the function of T-cells?
To produce cell-mediated immunity.
