Chapter 18 Flashcards
Whole Blood
Plasma and formed elements; separated into parts by a centrifuge
Erythrocytes
Red Blood Cells; 44% of whole blood; transport respiratory gasses in the blood; anucleated; short lifespan; packed with hemoglobin
Buffy Coat
Composed of leukocytes and platelets
Plasma
55% of whole blood; fluid portion of blood; contains plasma proteins and dissolved solutes; extracellular fluid; higher protein concentration to interstitial fluid
Leukocytes
White blood cells; defend against pathogens; immune system cells
Platelets
Thrombocytes; help form clots to prevent blood loss; anucleated; circulate for 8-10 days then broken down and recycled; membrane-enclosed cell fragments
Functions of blood
Transportation; protection; Regulation of body conditions; body temperature; body ph; fluid balance
Albumins
Smallest and most abundant plasma proteins; exert the greatest osmotic pressure; act as transport proteins for some lipids, hormones, and ions;
Gobulins
alpha-gobulins are smaller; beta-gobulins are smaller; transport some water-insoluble molecules, hormones, metals, ions
Fibrinogen
makes up 4% of plasma proteins; contributes to blood clot formation
Regulatory Proteins
includes enzymes and hormones
Hematocrit
Volume of all formed elements; percentage of erythrocytes; Males have a slightly higher percentage than females due to testosterone
Hemopoiesis
production of formed elements; occurs in red bone marrow
Hemocytoblasts
Blood stem cells
Pluripotent
can differentiate into many types of cells; Myeloid line and lymphoid line
Myeloid Line
forms erythrocytes, and all leukocytes except lymphocytes
Lymphoid Line
forms only lymphocytes
Colony-Stimulating Factors
stimulate hemopoiesis
Erythropoiesis
red blood cell production
Leukopoiesis
production of leukocytes
Thrombopoiesis
platelet production
Hemoglobin
red-pigmented protein; transports oxygen and carbon dioxide; Composed of four globins; oxygen bonds to iron weakly; carbon dioxide binds to globin protein weakly
Agglutination
Caused by incompatible blood transfusions; recipient antibodies bind to erythrocytes and clump them together;
Granulocyte
has granules with enzymes that are released (Neutrophil, eosinophil, basophil)
Agranulocyte
No granules; lymphocyte and monocyte
Neutrophils
50-70% of total leukocytes; phagocytize pathogens; granulocyte
Basophils
Release granules containing chemicals that attract immune cells; granulocyte
Eosinophils
Phagocytize antigen-antibody complexes and parasites; granulocyte
Monocytes
2-8% of total leukocytes; exit blood vessels and become macrophages; phagocytize pathogens and cellular fragments; agranulocyte
Lymphocytes
20-40% of total leukocytes; coordinate immune cell activity; attack pathogens and abnormal and infected cells; produce antibodies; adaptive immunity; agranulocyte
T-lymphocytes
effective against antigen within cells; requires antigen-presenting cell
B-lymphocytes
effective against antigen outside cells; does not require antigen-presenting cell
Natural Killer Cells
Destroy unhealthy and unwanted cells by releasing cytotoxic chemicals
Hemostasis
stoppage of bleeding; vascular spasm, platelet plug formation, coagulation phase