Chapter 17 Flashcards
Study Guide
What is a Prion
A proteinaceous infectious particle
Misshaped protein changes normal protein into misshaped protein.
Seen in CWD, Mad Cow, and Creutzfeld Jakob Disease
What is a Viroid?
Naked strands of RNA that take over cells to make more viroids
Seen in plants
What components make up a virus
Outer Capsid- Composed of protein subunits
Inner Core- Viral genome with DNA & RNA
What are the 5 Stages of the viral Cycle?
Attachment Penetration Biosynthesis Maturation Release
What happens in Attachment
Capsid combines with a receptor in the bacterial cell wall
What happens in Penetration
A viral enzyme digests away part of the cell wall and viral DNA is injected into the bacteria cell
What happens during Biosynthesis
Viral components begins after the virus inactivates host genes. Machinery of the host cell then carries out viral DNA replication
What happens during Maturation
Viral DNA and capsids assemble to produce several hundred viral particles
What happens during Release
Release of the phage particles. Bacteria Cell Dies
What happens in Lytic Vs Lysogenic Viral Cycles
Lytic is Attachment, Penetration, Biosynthesis, Maturation, Release.
Lysogenic phase a affected bacterial cell doesnt immediately produce phages, but might later. Following penetration, integration occurs. Viral DNA becomes incorporated into bacterial cell DNA with no destruction of host. Can re-enter lytic stage at any time.
Why dont antibiotics work on viruses?
Because they specifically target the bacterias machinery, which they cannot find after it has been taken over by a virus
What is a Retrovirus
Viruses that use RNA as their genetic material
How does the cell cycle work in a retrovirus
Enters the cell, reverse transcript converts retroviral RNA into DNA. Viral DNA then goes to nucleus and becomes intergrated into host genome. Can exit cell and infect another. (HIV)
Structure of a prokaryotic cell
No nucleus or other membrane bound organellles
2 domains with prokaryotic cells
Archaea
Bacteria