Chapter 16: Lymphatic System Flashcards

1
Q

lymph nodes

A

found in groups or chains along the paths of larger lymphatic vessels through the body; contain lymphocytes and macrophages

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2
Q

what do lymphocytes do?

A

attack viruses, bacteria, & parasitic cells

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3
Q

what do macrophages do?

A

engulf & destroy foreign substances, damaged cells, & cellular debris

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4
Q

major lymph node locations (7)

A
  • cervical
  • axillary
  • inguinal
  • supratrochlear
  • pelvic
  • abdominal
  • thoracic
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5
Q

where are lymph nodes NOT located?

A

CNS

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6
Q

lymph node function

A
  • filter harmful particles from lymph
  • immune surveillance; monitor body fluids
  • center for lymphocyte production
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7
Q

thymus

A
  • soft, bilobed
  • in mediastinum
  • divided into lobules
  • T cells
  • thymosin
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8
Q

t cells

A

mature in thymus; leave thymus and provide immunity

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9
Q

thymosin

A

hormone produced by thymus; stimulate t cells

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10
Q

lobules (thymus)

A

contain lymphocytes derived from progenitor cells in red bone marrow

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11
Q

spleen

A

largest lymphatic organ, contains venous sinuses filled with blood, filters blood

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12
Q

2 tissue types (spleen)

A
  • white pulp
  • red pulp
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13
Q

white pulp

A

lymphocytes

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14
Q

red pulp

A

rbc’s, lymphocytes, macrophages

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15
Q

pathogens

A
  • disease causing
  • bacteria, viruses, complex microorganisms
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16
Q

innate defense

A
  • general defense
  • protect against many types of pathogens
17
Q

adaptive defense

A
  • known as immunity
  • more specific & precise, targeting specific antigens
  • carried out by lymphocytes that recognize certain foreign molecules
18
Q

types of innate defense (6)

A
  • mechanical barriers
  • chemical barriers
  • inflammation
  • fever
  • natural killer cells
  • phagocytosis
19
Q

species resistance

A

refers to the fact that certain species are resistant to diseases that affect other species

20
Q

mechanical barriers

A

skin & mucous membranes; prevent pathogen entrance, considered first line of defense
ex. saliva & tears

21
Q

chemical barriers include:

A
  • enzymes
  • interferons
  • defensins
  • collectins
  • complement
22
Q

enzymes

A

chemical barrier to pathogens
ex. gastric juices & lysozyme in tears

23
Q

interferons

A

block viral replication, act against growth of tumors, stimulate phagocytosis

24
Q

defensins

A

peptides produced by neutrophils; cripple microbes, by making openings in cell membranes/walls

25
Q

collectins

A

proteins that protect against many bacteria, yeast, & some viruses

26
Q

complement

A

group of proteins in plasma & other body fluid that stimulate inflammation, attracts phagocytes & enhances phagocytosis

27
Q

natural killer (NK) cells

A
  • small population of lymphocytes
  • very different from T & B cells that provide adaptive defenses
  • defend against viruses & cancer cells by secreting cytolytic substances
28
Q

perforins

A

secreted by natural killer cells, lyse cell membrane and defend against cancer cells & viruses

29
Q

inflammation

A
  • redness, swelling, heat, & pain
  • process that walls off infection site & inhibits spread of infection
30
Q

heparin & histamine

A

increases capillary permeability

31
Q

phagocytosis

A
  • removes foreign particles from lymph
  • in blood vessels & tissues of spleen, liver, or bone marrow remove particles from blood
  • most active are neutrophils & monocytes
  • chemotaxis
  • mononuclear phagocytic system
32
Q

chemotaxis

A

chemicals from damaged tissue attract the phagocytic cells to the injury

33
Q

mononuclear phagocytic system

A

reticuloendothelium; consists of monocytes & macrophages of the body

34
Q

fever

A

begins when viral or bacterial infection stimulates lymphocytes to proliferate, procduing cells that secrete IL-1 which raises thermoregulatory set point

35
Q

IL-1

A

endogenous pyrogen; fire maker from within

36
Q

what does high body temp do?

A

increases phagocytic activity

37
Q

dangerous temp

A

adult = 103
child = 105

38
Q

macrophages

A

tissue

39
Q

monocyte

A

blood