Chapter 12 Flashcards
Cell division
Reproduction of cells
Genome
A cells DNA , it’s genetic information
Chromosomes
Structures that DNA molecules are packed into Named bc they take up certain dyes used in microscopy Chroma - color, soma - body Each eukaryotic chromosome consists of one very long linear DNA molecule and many proteins
Chromatin
The entire complex of DNA and proteins that is the building material of chromosomes
Somatic cells
All human body cells except reproductive cells
Gametes
Reproductive cells such as sperm and eggs
Sister chromatids
Joined copies of original chromatids each containing an identical DNA molecule, attached by protein complexes called cohesins
Centromere
A region made up of a repetitive sequence In the chromosomal DNA where the chromatid is attached most closely to its sister chromatid
Mitosis
The division of genetic material in the nucleus
Cytokinesis
Division of the cytoplasm
May overlap telophase but is not part of mitosis
Meiosis
Yields daughter cells with only one set of chromosomes half as many as the parent cell In humans happens in special cells in ovaries or testes
Cell cycle
The life of a cell from being formed from parent cell to division to daughter cell
Mitotic (M) phase
Includes both mitosis and cytokinesis Shortest part of cell cycle
Interphase
Consists of G1 phase, S phase and G2 phase 90% of cell cycle
G1 phase
Metabolic activity and growth phase
synthesizes various enzymes and nutrients needed later for cell division
S phase
Duplication of chromosomes and cell continues to grow
*Check point in cell cycle*
Create replication origins
Starts to duplicate the DNA
G2 phase
Grows and completes preparation for cell division
- Cell copies organelles and prepares for division
- Check point - checks and repairs damaged DNA
What are the 5 stages of mitosis?
Prophase Prometaphase Metaphase Anaphase Telophase
Prophase
Each duplicated chromosome appears as two identical sister chromatids joined at their centromeres (not yet visible)
Mitotic spindle begins to form
Nucleoli disappear
Duplicated centrosomes begin to move to opposite sides of the cell
Prometaphase
Nuclear envelope fragments
Microtubules invade the nuclear area
Chromosomes become even more condensed
Kinetochore a special protein has formed at the centromere of each chromosome
Microtubules lengthen the cell
Centrosomes move to opposite side of cell