ch. 13 terminology Flashcards

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1
Q

virus

A

obligate intracellular parasites

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2
Q

basic components of viruses

A

biochemically dependent on the host cell

multiply successfully in living cells

no larger than 300nm

multiply by binary fission

do not contain both dna and rna

no ribosomes

limited metabolically

cannot multiply or make copies of themselves

not sensitive to antibiotics

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3
Q

viral tropism

A

virus ability to infect a specific cell or tissue

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4
Q

pantropic

A

affecting many types of tissues

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5
Q

incubation period

A

between time of exposure and first symptoms

virus enters body

infects lymph nodes

virus multiplies

produces viremia in the blood

virus spreads through the body and blood stream

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6
Q

Phase 2 of incubation

A

Disease– symptoms of a viral infection

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7
Q

acute infection

A

you either recover or die— appears suddenly and may be brief or prolonged duration

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8
Q

persistent infection

A

infection lingers for long periods of time

virus is not cleared but remains in specific cells of infected individuals

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9
Q

latent infection

A

lack of demonstrable infectious virus between episodes ( period of time during which no infection virus in produced) of recurrent disease

infectious agent present with no disease

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10
Q

chronic infection

A

virus is constantly being produced over a period of time

continued presence of infectious virus following the primary infection– may include chronic or recurrent disease

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11
Q

modes of virus entry

A

mouth

respiratory tract

nose

bite of arthropod (mosquito)

sexual interaction

broken skin –scratch

inoculation with a needle

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12
Q

virion

A

physical virus particle

nucleocapsid alone for some viruses (picornaviruses) or including outer envelope structure for others ( retroviruses)

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13
Q

capsid

A

regular shell-like structure composed of aggregated protein subunits which surrounds the viral nucleic acid

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14
Q

capsomere

A

morphological unit detected under electron microscope

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15
Q

nucleocapsid

A

CORE

viral nucleic acid enclosed by a capsid protein coat

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16
Q

envelope

A

VIRAL MEMBRANE

lipid bilayer containing viral glycoproteins

17
Q

what is the phospholipid bilayer derived from in viruses

A

the cell that the virus arose from

18
Q

not all viruses have envelopes so what do they only consist of

A

nucleocapsid

19
Q

sterilization

A

steam under pressure

dry heat

ethylene oxide

y-irradiation

20
Q

formulas used for disinfection

A

sodium hypochlorine

glutaraldehyde

formaldehyde

peracetic acid

21
Q

formulas used for skin disinfection

A

chlorhexidine

70% ethanol

iodophors

22
Q

formulas used for vaccine production

A

formaldehyde

B-propiolactone

psoralen +UV irradiation

detergents ( for subunit vaccines)