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FIIS > Cells of the Immune System > Flashcards

Cells of the Immune System Flashcards

1
Q

Which is the most abundant immune cell?

A

Neutrophils

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2
Q

Describe the appearance of a neutrophil

A

Multi-lobed nucleus

Contain granules

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3
Q

What are the functions of neutrophils?

A

Phagocytosis
Degranulation
Neutrophil Extracellular Trap

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4
Q

Describe how NETs work?

A

Neutrophils release condensed chromatin and granule contents

This captures and kills bacteria

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5
Q

Where are eosinophils found?

A

In connective tissue under epithelium in the respiratory, GI and urogenital systems

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6
Q

What chemokine attracts eosinophils?

A

Eotaxin

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7
Q

What are the functions of eosinophils?

A

Release toxic granules: kill parasites and play a role in allergic reactions
Release chemical mediators which increase inflammation

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8
Q

Which cell is the least common granulocyte?

A

Basophils

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9
Q

What is contained in the cytoplasmic granules of basophils?

A 
IgE
Cytokines
Histamine
Heparin
Proteolytic enzymes
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10
Q

Where are mature mast cells found?

A

On surfaces exposed to pathogens and allergens

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11
Q

What are mast cells activated by?

A

IgE

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12
Q

Describe the nucleus of a mast cell

A

Round

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13
Q

Describe the nucleus of a basophil

A

Lobated

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14
Q

What are the largest immune cells?

A

Monocytes

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15
Q

Where are monocytes found?

A

50/50 between blood and spleen

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16
Q

What is found in the cytoplasm of monocytes?

A

Lysosome vesicles

17
Q

What are the functions of monocytes and macrophages?

A

Phagocytosis
Antigen presentation to T cells
Cytokine production

18
Q

What are dendritic cells in the skin known as?

A

Langerhans cell

19
Q

Where are mature dendritic cells found?

A

Lining of nose, lungs, stomach, intestines

20
Q

What are the functions of dendritic cells?

A

Phagocytosis
-activates the DC and it migrates to the lymph nodes
Antigen presentation in the lymph nodes

FIIS (24 decks)

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