Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

FIIS > 17. Atopy and Allergy > Flashcards

17. Atopy and Allergy Flashcards

1
Q

What is atopy?

A

Genetic tendency to make IgE
Autoantibodies are produced to receptors on mast cells
Manifests as rhinitis, asthma and eczema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is urticaria caused by?

A

Superficial histamine release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is angioedema caused by?

A

Deep histamine release or bradykinin build up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is dermographism?

A

Extreme urticaria which can be brought on by friction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Chronic urticaria is caused by allergy. T/F?

A

False

Allergic symptoms will come on within 1 hour of exposure to the antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is an allergy?

A

History of allergic reactions to a substance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the difference between sensitisation and allergy?

A

In sensitisation specific IgE is present without symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why should someone who is sensitive to a food not cut it out of their diet?

A

By eating it regularly, they maintain tolerance to it, cutting it out could cause the allergy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How is an allergy diagnosed?

A

History
Skin prick test
Allergen specific IgE
Food challenge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How should anaphylaxis be managed?

A 
Assess ABCs
Lie flat
Oxygen
Adrenaline IM
Antihistamine
Hydrocortisone IV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the purpose of giving hydrocortisone to treat anaphylaxis?

A

Prevent the late phase of the reaction

Eosinophils are sensitive to steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What determines the severity of an allergic reaction?

A

Dose of allergen
Asthma status
Exacerbating factors
ACE inhibitors and beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the hereditary causes of C1 inhibitor deficiency?

A

Type 1: too little protein

Type 2: dysfunctional protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the acquired causes of C1 inhibitor deficiency?

A

Consumption

Autoantibody

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What proteins should be measured to diagnose a C1 inhibitor deficiency?

A

C1 inhibitor
C1q
C4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does C1 inhibitor deficiency present?

A

Angioedema due to increased bradykinin

17
Q

How is C1 inhibitor deficiency treated?

A

c1 inhibitor

block bradykinin

18
Q

What is the cause of atypical urticaria?

A

Vasculitis

19
Q

What questions are important in an allergy focused history?

A 
What happened?
When did it happen?
What did you eat 1-2 hours before?
General circumstances
What treatment was needed?
Any repeat exposure?

FIIS (24 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions