Causes Of Disease- Overview Flashcards

1
Q

What does eitology mean?

A

Causes of disease

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2
Q

What are idiopathic diseases?

A

Conditions with no known cause

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3
Q

What are intrinsic conditions?

A

(From within)

Changes in an individual genome

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4
Q

Give some examples of intrinsic conditions

A

Nuclear or mitochondrial, inherited or de novo mutations and epigenetic modifications

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5
Q

What are cell autonomous intrinsic changes?

A

Cell X no longer expresses structural protein Y so cell X is the wrong shape

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6
Q

What are cell non-autonomous intrinsic changes?

A

Cell X no longer secretes protein hormone Y so cell Z no longer functions

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7
Q

What are some extrinsic causes of conditions?

A

Injury, infection, nutrition and diet, lifestyle (smoking, workplace toxins), chemical poisoning, exposure to radiation

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8
Q

What are the grey areas in causes of disease?

A

Intrinsic/ extrinsic areas can be ambiguous and subjective

Causes of disease are often a chain of events

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9
Q

When is age an intrinsic cause?

A

When it describes the biological process of ageing

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10
Q

What is a synonym for intrinsic?

A

Genetic

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11
Q

What is a synonym for extrinsic?

A

Environmental

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12
Q

When are genetic/environmental used instead of intrinsic/extrinsic?

A

When they are more reflective of that disease

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