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Physiology II > Cardiovascular system pt 5 > Flashcards

Cardiovascular system pt 5 Flashcards

1
Q

What is the O2 consumption levels at rest and 100% VO2 max?

A

11mL/kg min

93 mL/kg min

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2
Q

What is the Hr at rest and 100% Vo2 max?

A

125 bpm

279 bpm

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3
Q

What is the Q at rest and 100% VO2 max?

A

5.2

17

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4
Q

What is the avO2 at rest and 100% VO2 max?

A

5.2

13

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5
Q

What is the sys BP at rest and 100% VO2 max?

A

139

198

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6
Q

What is the dia BP at rest and 100% VO2 max?

A

85

71

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7
Q

What is the MAP at rest and 100% VO2 max?

A

111

131

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8
Q

What is the SVR at rest and 100% VO2 max?

A
  1. 9

7. 9

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9
Q

What is the Lactate concentration at rest and 100% VO2 max?`

A
  1. 8

3. 7

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10
Q

Which factors increase linearly at exercise?

A

VO2, HR, Q, Sys BP, and MAP

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11
Q

Which factors increase in a curvilinearly during exercise?

A

SV and avO2

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12
Q

Which factors decrease during exercise?

A

SVR and Dia BP (sometimes stays the same)

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13
Q

Why does Hr increase?

A

Parasympathetic withdrawal and Sympathetic activation

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14
Q

What causes SV to increase during exercise?

A
  1. Preload is increased due to increased venous return and vasoconstriction
  2. Afterload is increase due to increased sys BP which has a neg. effect on SV
  3. Contractility is increased due to increased beta 1 stimulation
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15
Q

What limits LVEDP in the frank starling relationship?

A

Pericardium prevents LVEDP from increasing past a certain point. Can be stretched with exercise training

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16
Q

What is responsible for an increased cardiac output during mild exercise?

A

Increase in HR and SV

17
Q

What is responsible for an increased cardiac output during hard exercise?

A

Mostly due to an increased HR

18
Q

Why does avO2 increase during exercise?

A

CaO2 does not change but CvO2 goes down because more oxygen is being used in the muscles.

19
Q

Why does CvO2 decrease in a curvilinear fashion?

A

Muscle recruitment
Capillarity of muscles
Mitochondrial density

20
Q

What happens to Sys BP during exercise?

A

It is raised and dependent on Q

21
Q

What happens to Dia BP during exercise?

A

It decreases and is dependent on SVR

22
Q

What happens to the SVR in the kidneys and splanchnic organs during exercise?

A

increases

23
Q

What happens to the SVR in the skeletal muscles during exercise?

A

It decreases

24
Q

What is the most important vasodilator at the beginning of exercise?

A

NO

25
Q

What is the most important vasodilator later in exercise?

A

Vasodilators especially adenosine

26
Q

What is sympatholysis?

A

Vasodilator metabolites are released and cause vasodilation and when they come into contact with sympathetic nerves inhibit the release of NE. This reduces vasoconstriction in working muscles

27
Q

What happens to muscles during exercise?

A

Blood flow increases

28
Q

What happens to blood flow to inactive muscles and organs?

A

Blood flow decreases, stomach has the largest drop

29
Q

What is the redistribution Q in muscles?

A

Rest 15% Exercise 80%

30
Q

What is the redistribution of Q in the kidney?

A

Rest 20% Exercise 2%

31
Q

What is the redistribution of Q in the splanchnic organs?

A

Rest 30% Exercise 3%

32
Q

Why do skeletal muscles see vasodilation during exercise when there is sympathetic innervation?

A

Vasodilator metabolites are released during exercise and stimulate vasodilation and win out over the sympathetic innervation

33
Q

What happens to NE levels as you exercise?

A

After reaching about 45% VO2 max it raises until it reaches 100% VO2 max. Levels of also rise the longer you exercise

34
Q

Sympathetic activation is…

A

Intensity and duration dependent

Physiology II (50 decks)

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