Carbs I Flashcards
What can glucose be made into via modification
proteoglycans, other glycosides
what can glucose produce bia the PPP
ribose, NADPH
what can glycose be used to make via glycolysis
pyruvate
oligosaccharides
less than 10 molecules are linked
polysaccharides
chains more than 10 molecules
beta configation
C1 hydroxyl group on the same side of ring
alpha confiration
C1 hydroxyl group on the opp side of the ring
mutarotation
in solution the alpha and beta form interconvert
what does mutarotation explain
damaging effects from teh reducing power of glucose.
in the open chain form waht can sugard do
reduce proteins
what happens when you oxidize the C1 hydroxyl group of glucose
initae the PPP
what happens if you oxidize the C6-hydroxyl group
yield uronic acid, which are important for proteoglycans in teh ECM
what does reduction of glucose yield
hexitol
what does oxiation of glucose yield
acids and ketones
what happens when you phosphorylate glucose
makes free glucose, which is found in extracellular fluids and enterocytes
what happens when you aminiate glucose
helps make UDP-GlcNAc
what does glucosamine synthesis start from
fructose 6 phosphate
where are sulfated sugars found
large proteoglycan molecules that make up ECM
what do sulfate groups add to the molecule
negative charge
formation of glycosidic bond mechanism
- sugar linked to nucleotide, requires ATP, to form NDP-sugar
- NDP-sugar transfers carb to target molecule, catalyzed by glycosyltransfase and does not require ATP
what are glycosidic bonds formed between
substrate and activated sugar nucleotide
what is UDP-glucose required for
synthesis of glyogen