Acid Base Flashcards

1
Q

What is the henderson hassalbach equativon

A

pH= Pka +log (A-) /(HA)

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2
Q

what is the normal blood pH

A

7.35 - 7.45

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3
Q

what is the noraml cytoplasmic pH

A

6.9- 7.4

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4
Q

how is Correct pH maintained

A

chemical buffering
regulation of blood CO 2by lungs
regulation of blood HCO3 by kidney

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5
Q

what is the faster way to maintain correct pH

A

chemical buffering

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6
Q

what is the slowest way to maintain correct pH

A

regulation of blood HCO3 by kindey

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7
Q

what is a buffer

A

soltuion of weak acid adn conguate base

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8
Q

if pH is equal to pKa then what

A

weak acid in 50% dissociated

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9
Q

if pH is less than pKa then what

A

acid form predominates

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10
Q

if pH is great than pKa then what

A

base form predominates

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11
Q

when do weak acids buffer best

A

at pH near their pKa

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12
Q

what does buffering capacity depend on

A

conc of weak acid adn cognate base

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13
Q

what is the main intracellular buffer

A

phosphate buffer system

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14
Q

what is the main buffer system in the blood

A

bicabonate CO2 buffer

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15
Q

an increase of PP of CO2 results in what

A

reduces pH

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16
Q

bicarb buffer system equation

A

pH = 6.1 + log(HCO3/CO2)

17
Q

what does Henry’s law do

A

relate conc of dissolved gas and partial pressure of that case

18
Q

acidemia

A

blood pH

19
Q

alkalemia

A

blood pH > 7.45

20
Q

acidosis

A

process tending to lower blood pH

21
Q

alkalosis

A

process tending to raise blood pH

22
Q

respiratory acidosis

A

acidosis due to increase pp of CO2

23
Q

metabolic acidosis

A

acidosis due to a decrease in HCO3

24
Q

respiratory alkalosis

A

alkalosis due to decrease pp of CO2

25
Q

metabolic alkalosis

A

alkalosis due to an incrase in HCO3

26
Q

examples of respiratory acidosis

A

asthma, bronchitis, obestiry, sedatives/anesthetics

27
Q

examples of repiratory alkalosis

A

anxiety/pain
high altitude
mechanical hyperventilation

28
Q

examples of metabolic acidosis

A

renal failure
methanol posioning
diabetic ketoacidosis

29
Q

examples of metabolic alkalosis

A

acute alkali admin
vomiting
gastric aspiration
diuretics