Capilary and lyphatics Flashcards
what are the functions of capilarys
- exchnage surfaces for nutriance perfusion
- thin walled = easy diffusion
- large CSA of capillary bed
- slow constant flow
What is the shape / size of the capilary important for
normally 1 RBC thick which enables the close contant to the cell wall = easy diffusion
What are the properties of the fenestrated capilary
Some leakage
- fenestranted endothelium (holes)
- basal lamina = continuous
- glomerulus of the kidney
From atreiol to venuole what is the flow pathway through capilarys
terminal arteriol -> vsaular shunt -> post capilary venuole
vasular shunt made rom = metaateriol +throughfair channel
off the vasular shunt = paths to capilary beds, precapilary sphinters around these
What are the three types of capilarys
Sinusoidal 30-40um
fenestrated 8-10um
continuous 8-10um
What are the properties of the continuous capilary
least leaky
- endothelium + basal lamina
- junction = intercellular celft
- basal lamina = continuous
- skeletal muscle
What are the properties of the sinusoidal capilary
very leaky
intracellular gaps in endothelium
discontinous basal lamina
- liver sinusoids
What are the different methods of transport from a capilary to tissue
-Passive diffusion - all
-bulk transport - all
-diffusion through intercellular celft all, tigh junction varys causes variable diffusion
-diffusion through fenestrations (not continuous)
what is the functions of lymphatics
- Drain tissues of excess fluid + plasma proteins
- fiter forign material
- innitate immune reponse
- absorb intertinal fats + return to vasuclar system
what is the structure of the lymphatic system
blind ended capilarys
contain valves
thin walls
large lumen
What is the lymphatics of the small intestine
vessles = lacteal to drain fat
vessles drain to cisterna chyli
Where do lymphnodes congregate + names of these regions
Axillary nodes = armpit
cervical nodes = neck
inguinal node = groin
What are the main drainage pathways from the lyphatic system
RHS upper body -> right lymphatic duct -> right sub clavicular vein
LHS upper + lower -> thorasic duct -> left sub clavicular vein
intestine -> lacteals -> ciasrerna chyli ->thorasic duct -> left sub clavicular vein
What is the function of lymph nodes
gain afferent lymph -> screen with immune cells -> release efferent lymph
What is the problem with brest lymph + cancer
brest cancer can become metastatic through the axillary lypmatics around the brest entering the blood flow and spreading, can be very dangerous. axillary lymphatics are checked during surgical removal for traces of cancer spread.
