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Pharmacology > C/18 Metronidazole, Fidaxomycine, Rifaximin > Flashcards

C/18 Metronidazole, Fidaxomycine, Rifaximin Flashcards

1
Q

Metronidazole

A

Anaerob bacteria and protozoons

Prosuces toxic intermediary metabolites in anaerobic conditions

Bactericidal

GI, neurologic, alcohol intolerance

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2
Q

Fidaxomicin

A

Binds to sigma subunit of RNA polymerase

Narrow spectrum. Not absorbed orally

C.diff

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3
Q

Rifaximin

A

Rifampin derivative, inhibits RNA polymerase

Poor oral bioavailibility

Treats traveler’s diarrhea and hepatic encephalopathy

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Pharmacology (26 decks)

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