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pharmacology > C/10 Carbapenems, Monobactams, Beta-lactamase inhibitors > Flashcards

C/10 Carbapenems, Monobactams, Beta-lactamase inhibitors Flashcards

1
Q

Imipenem

A

Carbapenem. Parenteral

Resistant to beta-lactamases. Broad spectrum

Rapidly inactivated by dehydropeptidase in the proximal tubule - combined with inhibitor cilastatin.

Epileptogenic (seizures)

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2
Q

Meropenem

A

Carbapenem. IV

Good activity against gram neg aerobs.

Often combined with vaborbactam

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3
Q

Clavulanate

A

Lactamase inhibitor

Combined with amoxicillin

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4
Q

Tazobactam

A

Lactamas inhibitor.

Combined with Ceftolozane, Piperacillin

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5
Q

Vaborbactam

A

Combined with meropenem

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