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Pharmacology > B/31 Immunopharmacology: Antibodies and fusion proteins > Flashcards

B/31 Immunopharmacology: Antibodies and fusion proteins Flashcards

1
Q

5-fluorouracil

A

Antimetabolite: pyrimidine analog. Inhibition of thymidylate synthase

Iv. Short action

Myelosuppressionm mucositis, fever, cardiotoxicity

Anticancer treatment

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2
Q

Capecitabine

A

Antimetabolite: pyrimidine analog

Anticancer treatment

Diarrhea, handfoot syndrome, GI, BM suppression

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3
Q

Cytarabine

A

Antimetabolite: pyrimidine analog

No action against solid tumors

BM suppression, mucositis, GI

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4
Q

6-mercaptopurine

A

Antimetabolite: purine antagonist

ALL

BM suppression, GI, anorexia, hyperuricemia

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5
Q

Methotrexate

A

See prev

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6
Q

Pemetrexed

A

Antifolate

In combination with cisplatin

Anticancer treatment

BM suppression, rash, mucositis, GI, fatigue, hand foot syndrome

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Pharmacology (26 decks)

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