C/15 Macrolides, Ketolides Flashcards

1
Q

Clarithromycin

A

50S. Bacteriostatic. Macrolide

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2
Q

Roxithromycin

A

50S macrolide

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3
Q

Azithromycin

A

50S macrolide.

Does not inhibit hepatic enzymes

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4
Q

Telithromycin

A

Ketolide

Similar to macrolides, but higher acid stability and better antibacterial effect. Good in case of macrolide resistance

Better against S. pyogenes, S. pneumoniae, Staph, H. influenzae

Bacterial pneumonia

GI, QT, liver problems

Inhibits microsomal enzymes

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