B/28 NSAIDs, non-opioid analgesics, gout Flashcards by Kristine Wallem | Brainscape

Q

Metamizole

A

NSAID

Analgesic and antipyretic. Relaxes SM

Rarely agranulocytosis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Naproxen

A

NSAID

Long acting. More COX1

Analgesic, antiinflammatory

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Ibuprofen

A

NSAID

Short acting

Antiinflammatory and analgesic. Mostly COX1

Safer than ASA (can be used in children)

Special indication: to close Botallo duct

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Ketoprofen

A

NSAID

Short acting

Antiinflammatory, analgesic

COX1 mostly

LOX inhibitor as well

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Phenylbutazone

A

NSAID

Strong antiinflammatory

Only for severe inflammations and maximum for one week

Also available as a cream (obs allergic reaction)

High toxicity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Indomethacin

A

NSAID

Short acting. Strong antiinflammatory.

Mostly COX1

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Diclofenac

A

NSAID

Both COX1 and COX2

Antiinflammatory and analgesic. Cumulates in joints

Can be given to children

Elevates liver transaminases, increased CV risk

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Meloxicam

A

NSAID

Long acting. Antiinflammatory.

Mostly COX2

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Celecoxib

A

NSAID

Selective COX2 inhibitor

Antiinflammatory

May cause allergy (sulfa)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Paracetamol

A

Short acting. Analgesic, antipyretic

Hepatotoxic

OTC

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Colchicin

A

Relieves acute gout attack

Oral

High toxicity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Allopurinol

A

Gout prophylaxis

Inhibits XO

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Rasburicase

A

Prophylaxis for gout

Recombinant urate oxidase

Slow infusion

Allergy, fever

How well did you know this?

1

Not at all

2

3

4

5

Perfectly