A/28 2nd generation antipsychotic agents Flashcards

1
Q

Clozapine

A

D4, H1, alpha1 antagonist

Never causes Parkinson

BM suppression, cardiomyopathy, metabolic disorder, weight gain, anticholinergic effect, agranulocytosis, sedation, hypotension

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2
Q

Olanzapine

A

5HT2A, H1, alpha1 antagonist

Metabolic disorder, anticholinergic, sedation, hypotension, hyperprolactinemia

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3
Q

Quetiapine

A

5HT2A, H1, alpha1 antagonist

Metabolic disorder, anticholinergic effect, sedation, hypotension, hyperprolactinemia

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4
Q

Risperidone

A

5HT2A, H1, alpha1 antagonist

Parkinsonism! Hyperprolactinemia, hypotension

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5
Q

Tiapride

A

Selective D2 antagonist

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6
Q

Aripiprazole

A

D2 agonist, 5HT2A antagonist

Can cause akathisia

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7
Q

Cariprazine

A

D3 antagonist

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