brain structure Flashcards

1
Q

limbic system

A
  • collection of structured deep inside the brain
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2
Q

what behaviors is the limbic system linked to

A

aggression

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3
Q

amygdala

A

plays a central role in how an organism asses and responds to environmental threats and challenges

it is an important predictor of aggressive behavior

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4
Q
A
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5
Q

what research did Emi cocarro et al do to support the function of the amygdala

A
  • studied people with intermittent explosive disorder
  • patients were fMRI scanned while they viewed pictures of angry faces
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6
Q

what is intermittent explosive disorder

A

involves outbursts of extreme reactive aggression

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7
Q

results emi cocarro et al

A
  • patients showed high levels and of amygdala activity when viewing the faces
    -this wasn’t a response in non IED patients
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8
Q

why did IED patients respond to the angry faces this way

A
  • aggression and amygdala activity is linked
  • an angry face is an ecologically valid sign of a threat
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9
Q

what part of the brain determines aggression

A

orbitofrontal cortex (OFC)
located in prefrontal cortex

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10
Q

where is OFC

A

region of pre frontal cortex
above eye sockets

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11
Q

what does OFC do

A
  • play an important role in higher cognitive functions such as rational thinking and decision making
  • is thought to be involved in self control, impulse regulation and inhibition or aggressive behaviors
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12
Q

for patients with a psychiatric disorder which features aggression what activity of the brain is thought to be reduced

A
  • Activity of OFC
  • disrupts impulse control
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13
Q

what evidence supports function of OFC

A

raine et al

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14
Q

serotonin

A
  • neurotransmitter with widespread inhibitory effects on transmission between neurons in the brain
  • slows down neuronal activity
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15
Q

what are normal levels of serotonin in OFC associated with

A
  • a reasonable degree of self control
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16
Q

what will decreases levels of serotonin in OfC do

A
  • lead to more impulsive behaviors e.g aggression
17
Q

what did Matti Virkkunen do to support serotonin levels with aggressive behaviors

A
  • compared serotonin breakdown product in the cerebrospinal fluid of violent impulsive and non violent impulsive offenders
18
Q

matti virkkunen results

A

levels of serotonin product breakdown was significantly lower in impulsive offenders

19
Q

dopamine

A

neurotransmitter they had inhibitory effect in some areas of the brain and excitatory effects in others

20
Q

what is dopamine involved in

A

regulating motivated behavior and our experience of reward

21
Q

what does dopamines main influence on aggression comes through its interaction with

22
Q

donglu seo et al research supporting dopamine and serotonin links in brain

A
  • serotonin interactivity and dopamine over activity are linked with impulsivity and aggression
  • serotonin hypofunction is the primary cause of impulse aggression
23
Q

evidence on amygdala = dustin pardini et al

A
  • identified 56 males who had been part of a study when they were 6/7 years old and 20 years later were studied again
  • over the 20 yrs these men had consistently behaved aggressively, including criminal violence
  • using fMRI scans researchers found a strong negative correlation between aggression levels and amygdala volumes
24
Q

results Dustin Pardini which supports amygdala

A
  • can’t be explained by confounding variables or earlier aggression levels as they were controlled = supporting influence of amygdala
25
Q

correlational research - weakness for links between aggression and brain structure

A
  • a study will find links between high levels of aggression and brain function, dysfunction or structure
  • it’s impossible to establish whether are structure is cal cause or effect of aggression
26
Q

how can we overcome the weaknesses of correlational research for brain structure and aggression

A
  • by using drugs to increase serotonin activity
  • e.g patients given paroxetine have viewer and less electrical shocks to others
  • evidence for a link between aggression and serotonin beyond correlational findings
27
Q

application -
brain structure and aggression

A
  • gives us a better understanding of neural influences on aggression
  • serenics is a drug that has been developed to affect the brains serotonin system and decrease aggression with minimal side effects
  • useful as human aggression is the root of many personal,
    social and economic costs
28
Q

disadvantage - brain structure = reductionist

A
  • narrow focus on biological factors is reductionist
  • amygdala is not an inevitable cause of aggression it also depends on social,psychological and environmental factors
  • biological factors isn’t enough to trigger aggression
  • reductionist explanation doesn’t reflect the complexity of the causes of aggression
29
Q

conclusion

A
  • there’s food evidence for the role of brain structures such as the amygdala however conclusions from research can be limited as we can’t be certain that these brain structures cause aggression as other factors also contribute towards it
    but
    brain structures contribute to aggression