B3- immune system ( defence) Flashcards

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1
Q

What are 3 PHYSICAL defence mechanisms apart of the PRIMARY IMMUNE SYSTEM?

A

NOSE: hairs + mucus which trap substances that contain pathogens to prevent entry
SKIN: sebum (oils) coating skin
physical barrier between internal and external environment
EYES: eyelashes protect from dirt and provide physical barrier

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2
Q

What are 3 CHEMICAL defence mechanisms apart of the PRIMARY IMMUNE SYSTEM?

A

STOMACH ACIDE: bile neutralsies, optimum PH for protease, kills microorganisms
TEARS: contains an enzyme to break down + protect
MUCUS + CILIA: mucus traps pathogens, cilia beats mucus up away (protects lungs)

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3
Q

what are the 2 WBC that defend us against disease

A

PHAGOCYTES
LYMPHOCYTES

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4
Q

What is phagocytosis

A

-PATHOGEN binds to CELL MEMBRANE of PHAGOCYTE
-after a PIT is FORMED the phagocyte ENGULFS and DIGESTS pathogen
-pathogen is ABSORBED and DIFFUSED into WBC.

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5
Q

why is phagocytosis considered as a non-specific defence?

A

phagocyte will engulf ANY PATHOGEN.

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6
Q

what are lymphocytes made up off?

A

anti-toxins, anti-gens, anti-bodies

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7
Q

what is a antigen?

A

protein on surface of cell

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8
Q

what is a antibody?

A

protein produces by lymphocytes to recognise pathogen (through MEMORY CELL) to help clump together.

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9
Q

what is a antitoxin

A

protein produces to neutralise toxins produced by pathogen (BACTERIA)

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10
Q

why are lymphocytes highly specific?

A

as antigen have a binding site that fit specifically to the same specific antibody

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11
Q

what do lymphocytes differentiate into?

A

memory cells

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12
Q

what is a vaccine?

A

contains a dead or inactive form of a pathogen to cause antibody production and form memory cells.

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13
Q

what is the process of a vaccine?

A

-vaccine enters body
-lymphocytes produce antibody to fight pathogen
-pathogen destroyed
-now defences against pathogen
-defences= MEMORY CELL
-pathogen dies very quickly if enter body again

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14
Q

what is a painkiller a form of

A

willow tree

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15
Q

what is a aspirin a form of

A

mould

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16
Q

what is are digitals form of

A

foxgloves

17
Q

what are drugs tested for when being made?

A

dosage
toxicity
efficiency

18
Q

what are the steps of making a drug
(7 stages)

A

1)research + discovery: test on cells
2) preclinical testing: test on animals
3) clinical test: healthy patients
4)clinical test: small group patients
5) clinical test: big group of patients
6) placebo testing: patients don’t know who has taken drugs
7) double blind: doctors + patients don’t know