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2 - CPR (pulmonary) > Antiviral Drugs - cardiopulm. infections > Flashcards

Antiviral Drugs - cardiopulm. infections Flashcards

1
Q

What are 2 vaccines for the prevention of Streptococcus Pneumoniae?

A

Prevnar 13

Pneumovax 23

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2
Q

What are 2 vaccines for the prevention of Streptococcus Pneumoniae?

A

Prevnar 13

Pneumovax 23

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3
Q

What is the best Influenza prevention?

A

Influenza “flu” Vaccine

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4
Q

Are there any effective drugs for viral pneumonia due to Adenovirus, Parainfluenza or Respiratory Syncytial Virus?

A

NO

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5
Q

Influenza treatments are NOT substitutes for?

A

The Flu Vaccine

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6
Q

What are the 4 Influenza treatments?

A

Oseltamivir
Zanamivir
Peramivir
Baloxavir

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7
Q

What are the 4 Influenza treatments?

A

Oseltamirvir
Zanamivir
Peramivir
Baloxavir

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8
Q

MOA for Oseltamivir, Zanamivir and Peramivir?

A

(-) Neuraminidase to interfere with virion budding from the host cell

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9
Q

What are the common adverse effects of Oseltamivir?

A

N/V, warnings if chronic organ disease

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10
Q

How is Oseltamivir given?

A

Orally

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11
Q

How is Zanamivir given?

A

Oral inhalation

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12
Q

What are the common adverse effects of Zanamivir?

A

Bronchospasm and coughing risk

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13
Q

How is Peramivir given and what does that do to the half life?

A

IV - longer half life

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14
Q

MOA for Baloxavir?

A

(-) endonuclease activity to block viral replication

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15
Q

Baloxavir is a prodrug. What convert it to its active state?

A

UGT1A3

CYP3A4

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16
Q

What is a common adverse effect of Baloxavir and when is it not used?

A
  • Diarrhea

- Not used in pregnancy

17
Q

What is another drug that is no longer recommended, but was used for Influenza A only?

A

Amantadine

18
Q

Amantadine is no longer recommended. What strain of Influenza was it used for and what is used for today?

A

Influenza A

– Now used for Parkinson Disease

19
Q

The drugs to treat Influenza are used for what 2 purposes?

A
  • Speed up recovery by 1-2 days

- Prophylaxis for those at high risk for complications

20
Q

The drugs to treat Influenza are used for what 2 purposes?

A
  • Speed up recovery by 1-2 days

- Prophylaxis for those at high risk for complications

2 - CPR (pulmonary) (26 decks)

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