Anatomy 10 - Connective Tissue Flashcards

1
Q

Connective tissue consists of cells embedded in

A

Large quantities of extracellular matrix

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2
Q

The extracellular matrix is composed of

A

Protein fibres, amorphous ground substance and tissue fluid

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3
Q

What are the two categories of connective tissue

A

Soft connective tissue and hard connective tissue

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4
Q

Examples of soft connective tissue

A

Tendons, ligaments, mesentery, stroma of organs and dermis of skin

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5
Q

Examples of hard connective tissue

A

Bone and cartilage

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6
Q

How is the type of connective tissue determined

A

By the type and relative amount if cells and the extracellular matrix

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7
Q

Functions of connective tissue

A

Space filler, mechanical support, attachment, protection, highway for nutrients and innervation, fat store, calcium store and the site of many immunological defence reactions

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8
Q

What are the resident cells of connective tissue

A

Fibroblasts, adipose cells, osteocytes and chondrocytes

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9
Q

What are osteocytes

A

The cells of bones

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10
Q

What are chondrocytes

A

The cells of cartilage

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11
Q

What do fibroblasts produce/maintain

A

The extracellular matrix

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12
Q

What cell is involved in tissue repair

A

Fibroblasts

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13
Q

Types of fibres found within the extracellular matrix

A

Reticular and elastic fibres

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14
Q

What is ground substance

A

An amorphous, space occupying material made of huge unbranched polysaccharide molecules called glycosaminoglycans (GAGs)

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15
Q

What are GAGs bound to

A

Protein cores

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16
Q

What is a GAG bound to a protein core called

A

Glycoprotein

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17
Q

What is the function of adipose cells

A

Release fatty acid into the bloodstream to provide energy for other cells

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18
Q

Most common type of connective tissue

A

Loose CT

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19
Q

Characteristics of loose CT

A

Loosely packed fibres separated by abundant ground substances

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20
Q

Characteristics of dense CT

A

It is made up of densely packed bundles of collagen fibres

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21
Q

If the fibres of dense CT are aligned it is known as

A

Dense regular CT

22
Q

Example of dense regular CT

23
Q

If in dense CT the fibre bundles run in many directions it is known as

A

Dense irregular CT

24
Q

Example of dense irregular CT

A

Dermis of the skin

25
Characteristics of cartilage
It is semi-rigid, consists of scattered cells surrounded by an amorphous appearing extracellular matrix, it is deformable, permeable, cells are nourished by diffusion and they grow appositional and interstitially
26
Characteristics of bone
It is rigid, non-permeable, the cells within the bone are nourished by blood vessels that provide the matrix and they grow appositionally only
27
Functions of bone
Provide support, act as levers for movement, protection, calcium store and the site of haemopoiesis
28
What are the three types of cartilage
Hyaline, elastic and fibrocartilage
29
Where is hyaline cartilage found
Articular surfaces, tracheal rings, costal cartilage, epiphyseal growth plates and is the precursor to bone in the foetus
30
What is found in the extracellular matrix of elastic cartilage
Elastic fibres
31
Where is elastic cartilage found
In the pinna of the ear, epiglottis and auditory tube
32
What is fibrocartilage made up of
Dense regular CT, islands of cartilage cells and cartilage matrix
33
Where is fibrocartilage found
In the intervertebral discs, where tendons insert into bones and in the pubic symphysis
34
Cartilage surrounded by connective tissue is called
The perichondrium
35
What are the layers of the perichondrium
An outer layer of dense CT and associated fibroblasts | An inner chondrogenic layer
36
What does the outer layer of the perichondrium provide
Support
37
What does the inner layer of the perichondrium provide
It supplies nutrients to the whole of the cartilage
38
What is bone comprised of
Water, collagen, non-collagen proteins and calcium hydroxyapatite crystals
39
What do osteoblasts secrete
Collagen, GAGs, proteoglycans and other organic compounds
40
What are the secretions of the osteoblasts collectively known as
Osteoid
41
Function of osteoblasts
Bone forming cells found on the surface of developing bone
42
What are osteocytes
Bone cells trapped within the bone matrix
43
What are osteoclasts
Large, multinucleated cells found on the surface of bone
44
Function of osteoclasts
Bone reabsorption
45
What are osteoprogenitor cells
They are located on the surface of bones and serve as a pool of reserve osteoblasts
46
Inactive periosteum
No bone is being formed
47
Active periosteum
New bone is being formed
48
What happens to osteoprogenitor when new bone is being formed
They proliferate and differentiate into osteoblasts
49
What is the endosteum
A thin vascular membrane of connective tissue that lines the surface of bony tissue
50
Functions of the endosteum
Repair, remodel and grow bone