All- Proteins & DNA Flashcards

1
Q

What are the monomers that make up proteins?

A

Amino acids

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2
Q

What is a polypeptide

A

More than two amino acids joined together

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3
Q

What makes up proteins?

A

One or more polypeptide

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4
Q

What are the 3 parts of an amino acid

A
Carboxyl group
-
Amino group 
-
R group
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5
Q

By what sort of reaction are amino acids linked?

A

Condensation reaction

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6
Q

What bond is formed between amino acids?

A

Peptide bond

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7
Q

Describe primary structure

A

Number and sequence of amino acids in a polypeptide chain

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8
Q

What type of bonds are involved in secondary structure?

A

Hydrogen bonds

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9
Q

What are the two types of secondary structure

A

Or fold into beta pleated sheet

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10
Q

Describe Tertiary structure

A

More bonds are formed

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11
Q

What type of bonds are involved in tertiary structure

A
Ionic bonds
-
Disulphide bonds 
-
Hydrophobic interactions
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12
Q

For what type of proteins is the tertiary structure the final shape?

A

Proteins made of a single polypeptide chain

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13
Q

What kind of bonds hold together the primary structure

A

Peptide bonds

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14
Q

Describe quaternary structure

A

Way they assemble themselvs

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15
Q

Name 2 proteins that have quaternary structure

A

Collagen

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16
Q

What determines a proteins 3D structure?

A

Sequence of amino acids will determine what bonds are formed

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17
Q

What are the 2 types of 3D structure

A

Fibrous

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18
Q

Where are the hydrophilic heads in Globular proteins

A

Facing outside

Hydrophobic inside

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19
Q

Describe the structure of globular proteins

A

Multiple polypeptide chains

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20
Q

What is the result of the hydrophilic heads facing the outside for globular

A

Soluble in water so easily transported in fluids

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21
Q

Name a globular protein

A

Haemoglobin

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22
Q

Describe the structure of fibrous proteins

A

Tightly coiled into rope shape

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23
Q

What makes fibrous proteins strong?

A

Chains held together by lots of bonds

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24
Q

Because fibrous is strong where is it found?

A

Supportive tissue

Connective tissue

25
Function of DNA
Store genetic information
26
Main function of RNA
Transfer genetic material to ribosomes
27
DNA and RNA are polymers of ...
Nucleotides
28
3 parts of a nucleotide
``` Pentose sugar (5 C atoms) - Nitrogenous bass - Phosphate group ```
29
Where is the variation in nucleotides?
The base
30
What are the 4 bases of DNA
``` Adenine (A) - Thymine (T) - Cytosine (C) - Guanine (G) ```
31
What’s the difference in possible based between RNA and DNA?
Uracil (U) replaces thymine
32
What is a polynucleotide?
Polymer of nucleotides - DNA and RNA
33
How do DNA and RNA differ except for base and sugar?
DNA is 2 polynucleotide strands joined in a helix - RNA is a single strand
34
Where do nucleotides bond to each other?
Sugar- phosphate - Condensation reaction
35
How do polynucleotide strands join together in DNA
Hydrogen bonding between bases
36
What’s the specific format of bonding called
Complementary base pairing
37
What are the two bonding pairs
A-T C-G Means there’s always equal amounts of each complimentary nucleotide
38
How many hydrogen bonds form between each base
2 for A-T 3 for G-C
39
How is the double helix formed?
Two anti-parallel polynucleotide strands twist
40
Define a gene
A sequence of nucleotide bases that codes for the sequence of amino acids in a polypeptide
41
What codes for 1 amino acid
A triplet (3 based)
42
Why must DNA by copied to RNA for protein synthesis (transcription)
DNA is found in the nucleus but ribosomes are in cytoplasm - DNA is too large to move out of the nucleus so a section is copied to mRNA
43
How many commonly occurring amino acids are there?
20
44
How many amino acids can plants/ animals make
Plants: all as long as suitable nitrogen Animals: some and must obtain rest from diet
45
What are the amino acids required from our diet called?
Essential amino acids
46
What is the side chain of an amino acid also called
Residual (R) group
47
Describe structure of an amino acid
``` Amino group Carboxyl group Hydrogen R group - All attached to a central carbon atom ```
48
Chemical formula for amino acid
``` H O | || H-N—C— C-OH | | H R ```
49
Purpose of haemoglobin
Oxygen transport
50
Purpose of enzymes
Speed up chemical reaction
51
How would two amino acids be linked together?
A condensation reaction between amino group and carboxyl group to form a peptide bond
52
Describe hydrogen bonds
Weak bond - Add molecular stability if occurs frequently
53
Describe ionic bonds
Susceptible to changes in PH
54
Deceive disulphide bonds
Strong bonds between amino acids which have sulphur in their R group
55
What are surface membranes made of?
Phospholipids Proteins Carbohydrates Cholesterol
56
What are the 3 components of a mononucliotide
Phosphate group Pentose sugar (ribose or deoxyribose) Organic base
57
How are nucleotides liked?
Condensation reaction forms phosphodiester bond between pentose sugar and phosphate group
58
Describe how DNA is organised in a bacterial cell
1. Large circular DNA 2. Not associated with histone proteins 3. Small plasmids 4. Located in cytoplasm