AB Flashcards

1
Q

fluoroquinolone ?

A

per os : norfloxacine

IV/PO : ciprofloxacine, ofloxacine, moxifloxacine

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2
Q

mode d’action fluoroquinolone ?

A

bactéricides
pic
inhibe synthèse DNA bactérien en inhibant DNA gyrase et topoisomérase
résistance croisée entre les différents Quinolone

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3
Q

pharmaco des fluoroquinolone ?

A

bonne absorption orale
demi-vie 3-11h
diffusion tissulaire et ds GB excellent

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4
Q

spectre fluoroquinolone ?

A

large, aérobie +++ (sauf moxifloxacine)

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