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Portage Microbiology > 6.5 Viruses in Microbiology II > Flashcards

6.5 Viruses in Microbiology II Flashcards

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Biology 101 flashcards
1
Q

What is polio also known as?

A

poliomyelitis

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2
Q

What is a general description of polio virus?

A

single-stranded, non-enveloped RNA virus

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3
Q

What family of viruses does polio belong to?

A

pcionaviridae

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4
Q

What is considered the most significant small virus?

A

polio

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5
Q

Where does polio infect?

A

CNS/motor neurons

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6
Q

How does polio damage the CNS?

A

temporary or permanent paralysis of motor neurons in spinal cord and brainstem

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7
Q

When was the polio vaccine introduced?

A

1955

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8
Q

What does the oral polio vaccine contain?

A

live but weakened (attenuated) virus

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9
Q

Which provides higher immune protection: IPV or OPV?

A

IPV

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10
Q

What is the family of viruses for the flu?

A

orthomyxoviridae

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11
Q

What are the three common subtypes of the flu?

A

A, B, and C

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12
Q

What is the general description of influenza?

A

segmented, single stranded, enveloped, RNA virus

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13
Q

What are the most pathogenic of the influenza strand?

A

influenza A

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14
Q

What are the two key glycoproteins that the influenza viral envelope contains?

A

hemagglutins (HA) and neuraminidase (N)

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15
Q

What are hemagglutins?

A

heavily involved in the entry of the flu virus into a host cell

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16
Q

What are neuraminidase?

A

involved in budding and released of new viral influenza particles from host cell

17
Q

What are the common drug targets for the influenza therapeutic intervention?

A

HA and N

18
Q

How do we typically name influenza viruses?

A

based on which HA and N variant is expressed on the envelope

19
Q

What strain is responsible for the Asian flu epidemic in 1957?

A

H2N2

20
Q

Why cant the flu vaccine vaccinate against all flu strains?

A

too many variations on the HA and Ns that can be present

Portage Microbiology (53 decks)

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