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Bacte Lec (Overview) [Prelims 1] > 5.4.1 Gardnarella vaginalis > Flashcards

5.4.1 Gardnarella vaginalis Flashcards

1
Q

What is the characteristics of Gardnerella vaginalis?

A

Short
Coccobacillus

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2
Q

What reagent inhibits Gardnerella vaginalis

A

Sodium polyanethol sulfonate

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3
Q

What is the normal flora for G. vaginalis

A

Vaginal tissue

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4
Q

What is the clinical infection for G. vaginalis?

A

Bacterial vaginosis

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5
Q

What happens to the pH in Bacterial vaginosis?

A

> 4.5

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6
Q

Less commonly associated UTI

A

Bacterial vaginosis

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7
Q

What is the normal pH for vagina?

A

3.8-4.5

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8
Q

What other bacteria causes bacterial vaginosis?

A

Chlamydia trachomatis
Trichomonas vaginalis

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9
Q

What is the smell of discharge in bacterial vaginosis?

A

Fishy odor

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10
Q

What is the microscopic characteristics of G. vaginalis?

A

Pleomorphic
Gram variable
Coccobacillus

“Clue cells” in wet mount

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11
Q

What is the description of clue cell in G. vaginalis?

A

Sunny side up

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12
Q

What is the cultural characteristics f G. vaginalis

A

Pinpoint
Non-hemolytic (BAP)

Beta hemolytic in human Blood bilayer tween (HBT) agar

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13
Q

What is supplemented in HBT agar?

A

Tween 80

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14
Q

What is the media of choice for HBT?

(On Lower part of the base)

A

Colistin Nalidixic acid (CNA)
Amphotericin B

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15
Q

What is the media of choice for HBT?

(On Upper part of the base)

A

5% human blood

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16
Q

Enhances the production of Beta hemolysis of G. vaginalis?

Located on both bilayer

A

Tween agar

17
Q

What is the presumptive test for G. vaginalis?

A

Whiff test

18
Q

What do you do in whiff test

A

Smell the fish odor

19
Q

What is being added in whiff test before whiffing it

A

1 drop of 10% KOH to the vaginal washing

20
Q

What does KOH do in whiff test?

A

Releases the amine (Fish odor)

21
Q

What are the components of amines?

A

Putrescine
Cadaverine
histamine

22
Q

What is the treatment for G. vaginalis?

A

Metronidazole

Bacte Lec (Overview) [Prelims 1] (34 decks)

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