Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Bacte Lec (Overview) [Prelims 1] > 3.1.2 Neisseria gonorrhoeae > Flashcards

3.1.2 Neisseria gonorrhoeae Flashcards

1
Q

What are the virulence factor of N. gonorrhoeae?

A

Receptors to human transferrin

Outer membrane proteins
- Protein I (porB)
- Protein II (Opacity)
- Protein III (Reduction modified protein)

Pili

Capsule

Lipooligosaccharide (Endotoxins)

IgA protease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

This virulence factor binds to iron-carrying protein to steal the iron

A

Receptors for human transferrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the outer membrane protein for Neisseria gonorrhoeae?

A

Protein I (porB)
Protein II (Opacity)
Protein III (Reduction modified protein)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the genes for protein I in outer membrane that is being secreted by Neisseria meningitidis?

A

porA and porB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

An outer membrane proteins that is a protective against inflammation and serum complement mediated killing

A

Protein I (porB)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is membrane attack complex? (MAC)

A

IT is where the complement attacks or kills the infected cells that has infected by bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

An outer membrane protein that adheres to phagocytic and epithelial cells

A

Protein II (Opacity)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

An outer membrane that blocks host serum bactericidal IgG

(Block phagocytosis and response to lymphocytes which prevents in the production of antibodies)

A

Protein III (Reduction modified protein)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do you connect each outer membrane protein?

A

Protein II (Opacity) allows adherence of the bacteria to the phagocytes and the epithelial cell then the Protein I (porB) gene prevents MAC and inflammation which assist the Protein III (Reduced modified protein) to block phagocytosis and bactericidal and immune response leading to no production of antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the specific nutrient or growth requirement of N. gonorrhoeae?

A

Iron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pili has 5 distinct colony types?

A

T1 and T2 = Virulent
T3-T5 = no pili (Not virulent)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the function of pili

A

attachment to host
Prevents phagocytosis
exchange genetic material

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Outer membrane proteins that create a channel for nutrients to pass into and waste products to exit cell

A

Protein I (porB)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the function of capsule in N. gonorrhoeae

A

Prevents phagocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A virulence factor that mediates damage to body tissue and releases a outer membrane fragment (blebs)

A

Lipooligosaccharides or endotoxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the main vivo virulence factor of N. gonorrhoeae?

A

Lipooligosacchrides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is IgA protease?

A

Cleaves IgA mucosal surfaces

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What bacteria is the most sexually acquired from asymptomatic carriers

A

N. gonorrhoeae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

If female has N. gonorrhoeae?

A

Infection carrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

If male has N. gonorrhoeae

A

Symptoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What are the clinical infections for N. gonorrhoeae?

A

Gonococcal urethritis and cervicitis

Conjunctivitis (Ophthalmia neonatorum)

Gonorrhea

Perihepatitis (Fitz-Hugh-Curtis syndrome)

Disseminated gonococcal disease

Extragenital infections
- pharyngitis
- Anorectal infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the meaning of Gonorrhea?

A

Flow of seed
Clap from french word

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Untreated Gonococcal urethritis and Cervicitis will lead to?

A

PID (Pelvic inflammatory disease

Sterility

Ectopic pregnancy

Fitz-Hugh-Curtis syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

A vertically transmitted disease that can lead to blindness of a child or newborn

A

Conjunctivitis (Ophthalmia neonatorum)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Gonorrhea is a acute pyogenic infection of the?

A

Pharynx
Urogenital tract
Conjunctiva of the eye

(PUC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

In male, what is the incubation period of gonorrhea?

A

2-7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

In male, what is the MOT of gonorrhea?

A

Sexual contact

28
Q

What is the meaning of Acute pyogenic infection?

A

Presence of pus formation

29
Q

What bacteria is One of the leading cause of STD?

A

Chlamydia trachomatis

30
Q

What are other bacteria/virus cause STD?

A

N. gonorrhoeae
Chlamydia trachomatis

human papilloma virus

31
Q

What are the symptoms of gonorrhea in males?

A

Dysuria

32
Q

A painful and difficult urination due to urinal discharge

A

Dysuria

33
Q

What are the complication of dysuria?

A

Epididymitis
Urethral stricture
Prostatitis
infertility

(EUPI)

34
Q

A complication of gonorrhea where an inflammation of small coiled tube of testicles

A

Epididymitis

35
Q

A complication of gonorrhea where a narrowing of urethra

A

Urethral stricture

36
Q

A complication of gonorrhea where inflammation of prostate

A

Prostatitis

37
Q

Females has many as 50% asymptomatic (carriers)

A

TRUE

38
Q

What are the symptoms of gonorrhea in females?

A

Dysuria
Cervical discharge
Lower abdominal pain

39
Q

What are the complication in females with gonorrhea?

A

PID which leads to
- Sterility
- Ectopic pregnancy
- Fitz-Hugh-Curtis syndrome

40
Q

What is PID

A

an infection in 1 or more upper female reproductive organs

41
Q

What is the most common site of infection in gonorrhea in females?

A

Endocervix

42
Q

It is the inflammation of the Cervix

A

Cervicitis

43
Q

How to detect Cervicitis?

A

Papsmear

44
Q

A yellowish in color in Cervicitis

A

Vaginal discharge

45
Q

Why does PID lead to Ectopic Pregnancy?

A

Scarring of the fallopian tube

46
Q

A severe chronic inflammation of the liver capsule WITHOUT the involvement of liver parenchyma.

A

Fitz-Hugh-Curtis syndrome

(Perihepatitis)

47
Q

In perihepatitis, where does the adhesion occur?

A

Inbetween Liver capsule and parietal peritoneum

48
Q

How does the infection occur in Perihepatitis

A

Due to scarring of the fallopian tube, bacteria passes through the liver capsule

49
Q

What do you call the adhesion in perihepatitis?

A

Violin String

50
Q

What happens if the fallopian tube is scar?

A

Infertile

51
Q

What is the first thing you do if you received a sample with this disease?

A

Gram Staining

52
Q

Example of Disseminated gonococcal disease

A

Blood-borne dissemination

Gonococcal arthritis

53
Q

Majority of DGD/3-5% of men are asymptomatic due to what strains?

A

Arginine
Hypoxanthine
Uracil

54
Q

Blood borne dissemination is not recovered in Blood culture?

A

TRUE

55
Q

Blood borne dissemination, N. gonorrhoeae is inhibited by?

A

Sodium polyanethol sulfonate

56
Q

Gonococcal arthritis is also known as

A

Purulent arthritis

57
Q

Gonococcal arthritis is result from?

A

Disseminated gonococcal bacteremia

58
Q

What antimicrobial agent is useful in treating gonorrhea?

A

Penicillin

59
Q

It is an anti-coagulant to prevent the clotting of blood that is being
put in the blood culture bottle.

A

Sodium polyanethol sulfonate

60
Q

What to add in Blood culture if you want to support the growth of N. gonorrhoeae?

A

Gelatin

61
Q

What is the most common extragenital infections in men having sex with men?

A

Anorectal infections

62
Q

What is the disease of the newborns in Extragenital infection?

A

Ophthalmia neonatorum

63
Q

Inflammation of tonsils?

A

Gonococcal pharyngitis

64
Q

What is use to treat Ophthalmia neonatorum?

A

Erythromycin

65
Q

If Ophthalmia neonatorum is left untreated, it will lead to?

A

Blindness

66
Q

What is the mode of transmission for Ophthalmia neonatorum?

A

Vertical transmission

Bacte Lec (Overview) [Prelims 1] (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions