4.4.2 Bacillus anthracis

Question 1

A virulence facto that is resistant to host proteolytic enzymes

Answer 1

Glutamic acid capsule

Question 2

A virulence factor that requires protective antigen in order to initiate edema and kill host cell?

Answer 2

Exotoxin

Question 3

A binding molecule to Edema factor and lethal factor to initiate their response?

Answer 3

Protective antigen

Question 4

What contains in Edema factor?

Answer 4

Adenylate cyclase

Question 5

Edema factor + Protective antigen =?

Answer 5

Edema

Question 6

A protease that kills host cell

Answer 6

Lethal factor

Question 7

Lethal factor + protective antigen =?

Answer 7

Kill host cell

Question 8

What are the virulence factor for bacillus anthracis

Answer 8

Glutamic acid capsule
Exotoxins (EF and LF)

Question 9

What is the clinical infection for Bacillus anthracis?

Answer 9

Cutaneous anthrax
Pulmonary anthrax
Gastrointestinal anthrax

Question 10

What are the symptoms of Cutaneous anthrax?

Answer 10

Black eschar

Question 11

Who is most susceptible in Cutaneous anthrax?

Answer 11

Farmers

Question 12

Manifested by erythematous papule to ulceration and to formation of an eschar

Answer 12

Cutaneous anthrax

Question 13

Also known as wool sorters disease

Answer 13

Pulmonary anthrax

Question 14

MOT of Pulmonary anthrax?

Answer 14

Air droplet

Question 15

Most severe but less encounter form of anthrax

Answer 15

Gastrointestinal anthrax

Question 16

Most common but least severe form of anthrax

Answer 16

Cutaneous anthrax

Question 17

What is the MOT of Gastrointestinal anthrax

Answer 17

Fecal-oral/ingestion