3.1.6 Rapid identification Flashcards
What are the immunologic assays?
- Coagglutination
- Fluorescent antibody testing
- MALDI-TOF
Uses a monoclonal antibodies
(S. aureus)
Coagglutination
Monoclonal antibodies to Por proteins that attaches fluorescent tags
Fluorescent antibody
Identification by unique protein signatures of the organism
MALDI-TOF MS
Matrix-assisted-laser-desorption-ionization time of flight mass spectrometry
What are the advantages of nucleic acid assay?
Rapid
Sensitive
What are the disadvantage of nucleic acid assay?
Non-amplified probe tests are only marginally more sensitive than
cervical culture in women
Not approved for pharyngeal or rectal specimen
Why is pharyngeal or rectal specimen not approved in nucleic acid assay?
Nucleic acid assay is only intended for
- Cervical
- Urine
- Other urethral extubates
ITO also cannot identify N. gonorrhoeae infection produce by beta lactamase-producing strain
Wat is the medicine of choice for Neisseria spp?
Penicillin
A Neisseria that produces B-lactamase
Plasmid-mediated penicillinase-producing N. gonorrhoeae
In 2007, CDC recommended agains use of __________ for gonorrhea infection due to resistance
Fluoroquinolones
In 2010, what is the current recommended treatment for gonorrhea infection?
Cephalosporins
What antimicrobial to confirmed meningitis?
penicillin
What antimicrobial to confirmed meningococcemia?
Cephalosporins
Polysaccharide diphtheria toxoid conjugate vaccine
Menactra
Group 1 for commensal neisseria spp.
Pathogens
