5.1.1 Development Of The Brain 2 Flashcards
A program mechanism of cell death is called ____. It is distinct from necrosis, which is death caused by an injury or a toxic substance.
apoptosis
The brains system of over producing neurons and then applying apoptosis enables the CNS to ____ the number of incoming axons to the number of receiving cells.
match
When the sympathetic nervous system begins sending axons toward the muscles and glands, it doesn’t know the exact size of the muscles or glands. It makes ____ neurons than necessary and discards the excess.
more
The new growth factor is a ____, meaning a chemical that promotes the survival and activity of neurons.
neurotrophin
In addition to NGF, the nervous system responds to ____ ____ ____ ____ (BDNF) and several other neurotrophins.
brain derived neurotrophic factor
Neurotrophins are not necessary for survival of brain neurons, but they are ____ for growth of axons and dendrites, formation of new synapses, and learning.
essential
The early stages of brain development are ____. A mutation in one identified gene needs to any of a wide variety of defects in brain development.
critical
The developing brain is also highly vulnerable to ____, ____ ____, and ____ that would produce only mild problems at later ages.
malnutrition, toxic chemicals, and infections
The infant brain is highly vulnerable to damage by ____.
Alcohol
Children of mothers to drink heavily during pregnancy are born with ____ ____ ____, a condition marked by hyperactivity, impulsiveness, difficulty maintaining attention, varying degrees of mental retardation, motor problems, heart defects, and facial abnormalities.
fetal alcohol syndrome
Even in milder cases of fetal alcohol syndrome those were exposed to ____ alcohol show impairments in learning, memory, language, and attention.
prenatal
Alcohol suppresses of the release of ____, the brains main excitatory transmitter, and enhances activity of ____, the main inhibitory transmitter. Consequently, many neurons received less excitation and neurotrophins than normal, and they undergo apoptosis.
glutamate : GABA
Prenatal exposure to other substances can be dangerous too. On average, children of mothers to use cocaine or smoke cigarettes during pregnancy have an increased risk of ____ ____ and other behavioural deficits.
attention-deficit disorder
Children whose mother used antidepressants during pregnancy have increased risk of ____ ____.
heart problems
Finally, the immature brain is highly responsive to influences from the mother. ____ to the mother changes her behaviour in ways to change her offsprings behaviour. Children of impoverished and abused woman have, on average, increased problems in both the academic and social lives.
Stress