Sketchy - Macrolides

Question 1

Class: Azithromycin

Answer 1

Macrolide

Question 2

Class: Clarithromycin

Answer 2

Macrolide

Question 3

What is first line treatment for infection with Bordatella pertussis?

Answer 3

Macrolides

Close contacts need prophylaxis

Question 4

CAP by what bugs can effectivey be treated with macrolides?

Answer 4

Strep pneumo, H. flu, Moraxella

Question 5

Use what macrolide for atypical (walking) pneumonia as caused by Mycoplasma, Chlamydia and Legionella?

Answer 5

Azithromycin

Question 6

Besides doxycycline, what antibiotic is effective for urethritis and cervicitis caused by Chlamydia?

Answer 6

Azithromycin

Question 7

Clinical use in neonates: Erythromycin

Answer 7

Neonatal conjunctivitis and pneumonia caused by Chlamydia trach;
Neonatal conjunctivitis caused by Nesseria gonorrheae

Question 8

Azithromycin is indicated for what zoonotic disease?

Answer 8

Cat scratch fever - Bartonella henselae

Question 9

What is recommended treatment for Mycobacterium avium?

Answer 9

Macrolides - both azithromycin and clarithromycin

Question 10

Adverse effects: Macrolides

Answer 10

Diarrhea;
Acute cholestatic hepatitis –> jaundice;
Torsades strip, prolonged QT syndrome;
cytochrome P450 inhibition

Question 11

What is the triple therapy for H. pylori?

Answer 11

Clarithroycin
Amoxicillin
PPI