3.4 Flashcards

1
Q

What did Gregor Mendel discover

A

the basic underlying principles of heredity through his work on garden pea plants

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2
Q

What did Mendel experiments include

A

covering each flower until it could be hand fertilized with the pollen of a chosen parent plant, then examining the traits of the offspring

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3
Q

What three laws did Mendel discover (of inheritance)

A

The law of segregation

The law of independent assortment

The law of dominance

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4
Q

What does the law of segregation state

A

two alleles are separated during meiosis so that each gamete contains only one allele for each gene, alleles are passed from one generation to the next as distinct units

exceptions include genes on sex chromosomes and mitochondrial DNA which only inherited from the mtoher

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5
Q

Where is mitochondrial DNA inherited from

A

the mother

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6
Q

What is only inherited from the mother

A

mitochondrial DNA

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7
Q

What is the law of independent assortment

A

the allele inherited for one trait does not affect which allele will be inherited fro another trait . It is caused by random orientation

exceptions are for genes who’s loci are close together on the same chromosome - linked genes)

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8
Q

What are linked genes

A

genes who’s loci are close together on the same chromsoosm

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9
Q

What does the law of dominance state

A

if an organism has two different alleles, one allele will determine the trait The allele that determines the trait is dominant; the unexpressed allele is recessive 9 there are expceptions other than dominant- recessive, co-domincance)

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10
Q

What is DNA

A

the molecule that stores genetic information and short stretches of DNA that influence a particular characteristic (genes)

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11
Q

What does P/F1/F2 mean

A

used in specific breeding test in which two parents homozygous for different forms of a trait ar emitted

P - parental generation

F1 - first generation

F2 - second filial generation

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12
Q

What Is a phenotype

A

an organisms observable charvateristics or traits including its morphology and biochemical properties

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13
Q

What is a genotype

A

the two alleles present tin an organism for a particular gene

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14
Q

What is an allele

A

a particular version of a gene

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15
Q

What Is a dominant allele

A

an allele the has the same effect on the phenotype whether one or two copies are present

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16
Q

What is a recessive allele e

A

an allele that only has an effect on the phenotype when two copies are present

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17
Q

What are codominant alleles

A

alley that jointly affect the phenotype when present together, creating an intermediate or combined phenotype

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18
Q

A gene has three possible alleles. How many different genotypes can be found for this gene?

A

6

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19
Q

What is true of the law of segregation?

A

It refers to the fact that a parent has a pair of alleles for each gene, and will pass on only one to an offspring.

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20
Q

How many copies of alleles are present at each gene locus in a gamete produced by a diploid organism?

A

one - During gamete formation, the two alleles occurring at each gene locus of a diploid organism are separated to distribute one such allele per gamete.

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21
Q

What was the dominant and recessive allele in Mendel’s discovery

A
Y = yellow allele (dominant 
y = green allele (recessive)
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22
Q

What is said about dominant alleles

A

they always mask the effects of the recessive alleles, when both are present, only the dominant allele affects the phenotype

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23
Q

What is a Punnett grid

A

a diagram used to determine the expected ratio of genotypes and phenotypes in the offspring of parents with known genotypes

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24
Q

What does it mean when something is test crossed

A

crossed with a homozygous recessive

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25
What happens when two alleles are present in an individual
this leads to co-dominance and they are different phenotypes notation for the trait is in capital with capital superscript for the allele for example red coloru = CR white color = CW
26
How to find the probability of two independent events both occurring
multiply to find the probability
27
How do you find the probability that one event or another event occurs
you add them
28
What are the four main blood groups
A, B, AB, and O
29
What is the genotype for each blood type
IAIA or IAi - A IBIB or IBi - B IAIB - AB ii -O
30
What blood group alleles are co-dominant
I A and I B
31
What is the most safe blood group
O because it is the universal donor for blood transfusions
32
What antigens do each blood type produce
IAiA - lots of A IAi - a few A ii - nothing IAIB - A and B
33
Which can receive the least blood types
IA and IB
34
Which blood group phenotypes always has a homozygous genotype?
O
35
What is a rare allele
refers to the frequency of the allele and describes how many individuals in a population carry the allele
36
what is an autosomal disease
disease caused by the alleles in non sex genes
37
Name an example of an autosomal recessive disease
Cystic fibrosis
38
What is an example of a co-dominant autosomal disease
sickle cell anemia
39
What are sex linked diseases
diseases that are caused by certain genes on sex chromosomes
40
What is a y linked gene
follow a simple pattern because it is passed from the father to the sons and no daughters
41
What are x linked genes
females can be unaffected carriers of recessive alleles on the X chromosome, but since males have only one copy of the gene, they cannot be carriers. Recessive X linked diseases are seen much more frequently in males
42
If a genetic disease is caused by the recessive allele of a gene found on the X chromosome, it implies that:
male children are more likely to be affected by the disease
43
What is cystic fibrosis
an autosomal recessive disease caused by a mutation in the gene
44
What is Huntintogns disease
an autosomal dominant disease a neurodegenerative disorder that begins o affect people between 30 and 50 years of age. Cause by a mutation on the dominant gene
45
What is red green color blindness
a sex linked recessive disease XbY - affected male XBXb - unaffected mother 50% chance affected children for a female to have an X linked recessive trait, her father must also have the trait
46
What is hemophilia
a disease in which a protein needed for blood clotting most commonly, factor VIII I snot made. Meaning small injuries can cause patients to bleed excessively and die. recessive allele
47
Why are pedigree charts useful
they are good for studying inheritance in humans
48
what do you look for autosomal dominant
every affected individual has at least one affected individual both males and females affected seen in every generation
49
how do you identify for autumnal recessive
look for both males and females affected cases where two unaffected parents have an affected child skips generations
50
how to identify for sex linkage
usually only males are affected rarely seen but females affected only when the father is affected
51
What are two major causes of spontaneous mutations
Chemical mutagens and radiation
52
What do radiation and mutagenic chemicals do
they increase the mutation rate and can cause genetic diseases and cancer
53
What are mutagens
any agent that causes or increases the frequency of mutations by triggering changes in the genetic material of an organism
54
What types of radiation are mutagen
UV radiation, ultraviolet light, X rays)
55
What chemicals are mutagens
cigarette, smoke and food
56
What is radiation
occurs when energy, in the form of waves or particles is emitted.
57
What is the difference between the genetic material of gametes and zygotes?
Gametes have a single copy of an allele for each gene while zygotes have two copies for each gene.
58
The nuclear explosion at Chernobyl power station in 1986 caused an increase in cancers in surrounding areas. Which cancer was seen to increase dramatically in children following the explosion? (
thyroid
59
What is a characteristic of sex-linked inheritance in humans?
Men can only be hemizygous (only carry one copy) for the gene.
60
What could have been a valid conclusion on the basis of Mendel’s experiments?
Genes for two different characteristics are inherited separately.
61
A mutation in the CFTR gene causes cystic fibrosis. Which protein does this gene code for?
chloride channel in the mucous membrane.
62
How is red-green colour blindness inherited?
Affected girls must inherit the faulty allele from both parents.
63
Codominant alleles produce a new
phenotype