3.2 CHROMOSOMES Flashcards
PROKARYOTES
Prokaryotes have circular DNA without association of protein.
There is one copy of each gene except when the cell and its DNA are replicating
PLASMID IN PROKARYOTES
Plasmids are small separate (usually circular) DNA molecules located in some
prokaryotic cells
Plasmids are also naked (not associated with proteins) and are not needed for daily life processes in the cell.
PLASMID GENES
The genes in plasmids are often associated with antibiotic resistant and can
be transferred from one bacterial cell to another. ␣
USE OF PLASMID
Plasmids are readily used by scientists to artificially transfer genes from one
species to another (ie. Gene for human insulin)
PLASMID FEATURES (6)
Naked DNA without association of protein such as histone
Small circular ring of DNA
Not responsible for normal life process
Contain survival characteristics, e.g. antibiotic resistance
Can be passed on between bacteria
Can be incorporated into nucleoid chromosomes (save permanently)
EUKARYOTIC CHROMOSOMES
Eukaryotic chromosomes are linear and are made up of DNA and histone proteins.
HISTONES
Histones are globular shaped protein in which the DNA is wrapped around.
VARIATION OF EUKARYOTIC LINEAR CHROMOSOMES
length, centromere location and genes contained
NUMBER OF CHROMOSOMES IN HUMAN
23
NUMBER OF AUTOSOMES IN HUMANS
22
23RD PAIR
SEX CHROMOSOMES
WHAT DOES EACH CHROMOSOME CARRY?
specific sequence of genes along the linear DNA molecule
CHROMOSOME NUMBER AKA
‘N’ number
NORMAL CELLS CONTAIN
diploid nucleus
2N
two pairs of homologous chromosomes
SEX CELLS CONTAIN
haploid nucleus
N
one pair of homologous chromosome