3.14 Intoxicación por ATC Flashcards

1
Q

MDT ATC:

A
  • bloquean recaptura de NE y serotonina
  • anticolinérgico > midriasis, boca seca, taquicardia
  • bloqueo canales de Na cardiacos > arritmias
  • bloquea receptores alfa1 > hipotensión
  • bloquea receptores H1 > sedación
  • antagonistas GABA > convulsión
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2
Q

ATC + ISRS:

A

Sd serotoninérgico

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3
Q

Tx sd serotoninérgico:

A

Ciproheptadina

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4
Q

Fármacos más relacionados con convulsiones:

A

Clomipramina
Maprotilina

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5
Q

QRS < 100 ms:

A

No hay tanta clínica

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6
Q

QRS > 100 ms:

A

33% de los px convulsionan

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7
Q

QRS > 160 ms:

A

50% de los px generan arritmias

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8
Q

Cardiotoxicidad por ATC:

A

Torsades de pointes
Prolongación QRS, QT

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9
Q

Fármaco más relacionado con hipotensión y sedación:

A

Amitriptilina

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10
Q

Tx sobredosis por ATC:

A
  • Estabilizar al paciente (intubar si es necesario)
  • Carbón activado y lavado gástrico (casos graves)
  • Profilaxis arritmias, estabilizar QRS: bicarbonato de sodio
    Ventilación mecánica (casos severos)
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11
Q

Tx convulsiones:

A

Benzodiacepinas

No fenitoína

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12
Q

Tx arritmias:

A

Lidocaína, sulfato de magnesio, isoproterenol

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13
Q

Tx acidosis metabólica:

A

Bicarbonato de sodio (IV)

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14
Q

DT ATC:

A

5-15 mg en niños
10-20 mg en adultos

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15
Q

Causa #1 mortalidad por ATC:

A

Cardiovascular: hipotensión + taquicardia/ fibrilación ventricular

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16
Q

Causa #2 mortalidad por ATC:

A

Neurológicas: convulsiones, delirio, disminución de conciencia, sedación, alucinación

17
Q

Dx intoxicación ATC:

A

HC
EKG: prolongación del QRS, AVR y ondas R normales
Concentración de ATC