3/16/17 Salivary Gland Development BAKER TEST #3 Flashcards
When do you make the most saliva in your mouth?
When you are chewing food
How much saliva do we produce a day?
.5 Liters a day
T/F Salivary glands come from the oral epithelium
True
What do the majority of people believe the dermal origin of salivary glands are that arise from oral epithelium?
Ectodermal origin
What are the five stages of salivary gland development in a mouse?
- Prebud
- Initial bud
- Pseudoglandular
- Canalicular
- Terminal Bud
If you have salivary mesenchyme + mammary epithelium (nasal or pituitary) what will that =?
Salivary gland pattern (secretes milk, or hormones from the pituitary but it looks like a salivary gland)
If you have salivary gland E13 + Mammary mesenchyme (mandibular arch limb bud) what will that =?
-Failure to branch of the salivary gland
What is branching morphogenesis controlled by?
-Salivary mesenchyme
If the salivary gland formation lacks what factor will it not develop?
-Fgf2b
If you take salivary epithelium alone will the salivary gland develop?
-No
If you take the salivary epithelium and what will you get the development of the salivary gland?
-Salivary mesenchyme or Matrigel
What type of hydrogels promote salivary gland regeneration?
-L1 Peptide conjugated fibrin
What is released from the otic ganglion and the submandibular ganglion to give parasympathetic innervation to the SMG the parotid gland, and the sublingual gland?
-Acetylcholine
What is released by efferent nerves arising from the superior cervical ganglion away from the gland to give sympathetic innervation to the salivary glands?
-Norepinefrine
What salivary gland does the otic ganglion innervate?
-Parotid
