2/7/17 Dr. Dsouza Test #2 Tooth Development Flashcards

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1
Q

In the bell stage of development the continued differentiation of the enamel organ produces what four distinct layers?

A
  • Outer enamel epithelium
  • Stellate reticulum
  • Stratum intermedium
  • Inner enamel epithelium
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2
Q

What is the portion of tooth development is responsible the all the future periodontium?

A

-Dental follicle

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3
Q

What is the cervical loop?

A

The junction of the OEE and IEE

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4
Q

What is the function of the outer enamel epithelium?

A

-Protective barrier for enamel organ

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5
Q

What is the function of the stellate reticulum?

A

-Supports enamel production

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6
Q

What does the IEE differentiate into?

A

-ameloblasts

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7
Q

What is the function of the stratum intermedium?

A

-supports enamel mineralization

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8
Q

What does the DEJ form after?

A

-Disintegration of basement membrane

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9
Q

What type of enamel is formed by early secretory ameloblasts?

A

-Prismless enamel

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10
Q

What type of enamel is formed by Tomes processes or late secretory ameloblasts?

A

-Enamel prisms

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11
Q

Name the only ectodermally derived structure in the tooth?

A

-Enamel

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12
Q

Apposition and maturation of dentin and enamel occur in increments from where?

A

-The cusp or incisal tip

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13
Q

The apposition and maturation of dentin and enamel from the incisal or cusp tips occur in what direction?

A

-Cervical direction

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14
Q

After the deposition and initial mineralization of enamel, what do secretory ameloblasts lose?

A

-Tomes process

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15
Q

When does the Reduced enamel epithelium form?

A

-After enamel is fully matured

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16
Q

What two layers can you find in the REE?

A
  • OEE

- IEE

17
Q

When does dentin mineralize?

A

-AS it is deposited

18
Q

The initial mineralization of dentin is in the form of globules ultimately producing what?

A

-Globular dentin

19
Q

What is the initial layer of dentin next to the DEJ called?

A

-Mantle dentin

20
Q

What is remaining dentin around the pulp called?

A

-Circumpulpal dentin

21
Q

In the circumpulpal dentin what direction are the collagen fibers in comparison to the DEJ?

A

-Parallel

22
Q

In the mantle dentin the collagen fibers are oriented in what direction to the DEJ?

A

-Perpendicular

23
Q

Which layer of dentin has higher mineral content?

A

-Mantle dentin

24
Q

What becomes Hertwig’s epithelial root sheath?

A

-Root Dentin

25
Q

When the Hertwig’s epithelial root sheath detaches from root dentin and disintegrates what do they become?

A

-Epithelial rests of Malassez

26
Q

What is the organic matrix that cementoblasts secrete?

A

-Cementoid

27
Q

How do you get multiroot development?

A

The Hertwigs eipithelial roots sheath splits into two or three sheaths

28
Q

When the dental sac ectomesenchyme cells differentiate into fibroblasts what can they form?

A

-Periodontal ligament

29
Q

When the dental sac ectomesenchyme cells differentiate into osteoprogenitor cells what can they form?

A

-Osteoblasts to lay down alveolar bone

30
Q

Where do developing collagen fibers of the PDL become anchored?

A

-Alveolar bone

31
Q

What are five important molecules in embryonic development?

A
  • TGF B family
  • Fibroblast GF family
  • Hedgehog protein
  • Wnt family
  • Negative regulators of BMP signalling
32
Q

What are protooncogenes?

A

-Normal genes which direct formation of various molecules

33
Q

What are the two theories of tooth development?

A
  • Field Theory

- Clone Theory

34
Q

What does the field theory of development include?

A

-The tooth doesn’t know what it is going to become until it gets to its “field” that “tell” it what to do

35
Q

At the Lamina and bud stage what is inductive?

A

-Dental epithelium

36
Q

At the Cap and Early Bell stages what is inductive?

A

-Dental papilla Mesenchyme

37
Q

In the later stages of tooth development such as the early bell stage what determines the shape of the tooth?

A

-Dental papilla mesenchyme

38
Q

If at the later stages of tooth development such as during the early bell stage and you take molar mesenchyme and incisal epithelium what will grow?

A

-Molar

39
Q

If at an early stage of tooth development such as the Bud Stage and you take a molar mesenchyme and an incisal epithelium what will grow?

A

-Incisal