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Oral Biology 2020 > 2/28/17 Dentin Pulp Complex II TEST #3 > Flashcards

2/28/17 Dentin Pulp Complex II TEST #3 Flashcards

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1
Q

What does the dental pulp arise from?

A

-Dental papilla (Ectomesenchymal tissue)

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2
Q

What are the four histological zones of the pulp cavity from outer to inner?

A
  • Odontodblast layer
  • Cell free zone of Weil
  • Cell rich zone
  • Pulp Core
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3
Q

What is the primary cell type that you will find in the pulp?

A

-Fibroblasts

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4
Q

What are five support structures for the mineralized components of the tooth?

A
  • Blood vessels
  • Innervation
  • Fibroblasts
  • Pool of immune cells
  • Pool of progenitor cells
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5
Q

What do you find in the cell free zone of Weil?

A
  • Blood vessels

- Nerves

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6
Q

What type of collagen is mostly found in the Dental pulp?

A

-Collagen III

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7
Q

What are five proteoglycans found in pulp

A
  • Chonroitin -6-sulfate
  • Chondroitin-4-sulfate
  • Heparin sulfate
  • Dermatan sulfate
  • Keratan sulfate
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8
Q

What do proteoglycans sequester?

A

-Water

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9
Q

T/F With age, collagen content increases and fibrils aggregate into larger bundles, and you find the greatest concentration apically in the pulp.

A

True

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10
Q

What is the key dentin-pulp complex cell type?

A

-Odontoblasts

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11
Q

In odontoblasts you have an elongated nucleus at the pulpal side of the cell and the secretory components (Golgi bodies) towards what side?

A

-Dentinal side

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12
Q

What can Odontoblasts form gap junctions with?

A

-Pulpal fibroblasts

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13
Q

T/F Odontoblasts deal with the production and sequestration of key growth factors in dentin matrix.

A

True

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14
Q

When you have an aged odontoblast what is different with its structure and function compared to younger odontoblasts?

A
  • Fewer organelles
  • Less secretory activity
  • Nucleus is somewhat more central
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15
Q

What is the role of sequestered Growth Factors in the dentin matrix?

A

-Recruitment of new Odontoblasts

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16
Q

What is the predominant cell type in the dentin-pulp complex?

A

-Fibroblasts

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17
Q

What zones do you find fibroblasts in the pulp?

A
  • Pulp core

- Cell rich zone

18
Q

What type of progenitor cells are present in the dental pulp?

A

-Mesenchymal

19
Q

In response to damage to dentin, what cells are recruited to form new odontoblast-like cells?

A

-Dental pulp progenitor cells

20
Q

What immune cells do you find in the dental pulp?

A
  • Macrophages (Innate)
  • Dendritic cells (Acquired)
  • T and B lymphocytes
21
Q

Where does the pulp vasculature arise from?

A

-External carotid arteries from the Superior/inferior alveolar arteries

22
Q

How many arterioles do you find per root?

A

-4-8

23
Q

How do the arterioles access the root?

A

-Through the apical foramen

24
Q

T/F AS arterioles proceed into the pulp, caliber increases, and vessel wall decreases

A

True

25
Q

In the steady state of lymph flow, what is it equal to?

A

Lymph flow is equal to arterial interstitial flow

26
Q

When nerve fibers branch out through the coronal pulp what do they form?

A

-Plexus of Raschkow

27
Q

In the root pulp there are no what?

A

-Plexus of Raschkow

28
Q

What type of nerves do the incoming nerve fibers consist of?

A
  • Afferent nerves from the trigeminal

- sympathetic branches from the superior cervical ganglion

29
Q

T/F The nerve bundles consist of both myelinated Ad and unmyelinated C axons

A

True

30
Q

When does myelination decrease?

A

-AS fibers proceed towards the coronal pulp

31
Q

T/F Some unmyelinated nerve axons pass into the dentinal tubules and are closely associated with odontoblasts

A

True

32
Q

What are three proposed models of dentin sensitivity?

A
  • Direct innervation
  • Odontoblast nociception
  • Tubule fluid conductance
33
Q

There are nerves in some tubules goes with which proposed model of dentin sensitivity?

A

-Direct innervation

34
Q

Odontoblasts are neural crest derived, but anatomically do not synapse extensively with pulpal nerves goes with what proposed model of dentin sensitivity?

A

-Odontoblast nociception

35
Q

Local anesthetics applied to exposed dentin is ineffective, changes in fluid levels can cause sensitivity is associated with what model of dentin sensitivity?

A

-Hydrodynamic theory

36
Q

What are pulp stones?

A

-Mineralized tissue formed inappropriately in the pulp

37
Q

What is a true pulp stone?

A

-Contains tubules and they are associated with odontoblast-like cells

38
Q

What are false pulp stones?

A

-Consists of atubular mineralized tissue and sometimes with necrotic tissue at the center

39
Q

What do pulp stones often occur around?

A

-Collagen fibers

40
Q

As the tooth becomes less vital what happens to the tooth?

A

-It becomes more brittle

Oral Biology 2020 (21 decks)

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