2/28/17 Dentin Pulp Complex II TEST #3

Question 1

What does the dental pulp arise from?

Answer 1

-Dental papilla (Ectomesenchymal tissue)

Question 2

What are the four histological zones of the pulp cavity from outer to inner?

Answer 2

• Odontodblast layer
• Cell free zone of Weil
• Cell rich zone
• Pulp Core

Question 3

What is the primary cell type that you will find in the pulp?

Answer 3

-Fibroblasts

Question 4

What are five support structures for the mineralized components of the tooth?

Answer 4

• Blood vessels
• Innervation
• Fibroblasts
• Pool of immune cells
• Pool of progenitor cells

Question 5

What do you find in the cell free zone of Weil?

Answer 5

• Blood vessels

- Nerves

Question 6

What type of collagen is mostly found in the Dental pulp?

Answer 6

-Collagen III

Question 7

What are five proteoglycans found in pulp

Answer 7

• Chonroitin -6-sulfate
• Chondroitin-4-sulfate
• Heparin sulfate
• Dermatan sulfate
• Keratan sulfate

Question 8

What do proteoglycans sequester?

Answer 8

-Water

Question 9

T/F With age, collagen content increases and fibrils aggregate into larger bundles, and you find the greatest concentration apically in the pulp.

Answer 9

True

Question 10

What is the key dentin-pulp complex cell type?

Answer 10

-Odontoblasts

Question 11

In odontoblasts you have an elongated nucleus at the pulpal side of the cell and the secretory components (Golgi bodies) towards what side?

Answer 11

-Dentinal side

Question 12

What can Odontoblasts form gap junctions with?

Answer 12

-Pulpal fibroblasts

Question 13

T/F Odontoblasts deal with the production and sequestration of key growth factors in dentin matrix.

Answer 13

True

Question 14

When you have an aged odontoblast what is different with its structure and function compared to younger odontoblasts?

Answer 14

• Fewer organelles
• Less secretory activity
• Nucleus is somewhat more central

Question 15

What is the role of sequestered Growth Factors in the dentin matrix?

Answer 15

-Recruitment of new Odontoblasts

Question 16

What is the predominant cell type in the dentin-pulp complex?

Answer 16

-Fibroblasts

Question 17

What zones do you find fibroblasts in the pulp?

Answer 17

• Pulp core

- Cell rich zone

Question 18

What type of progenitor cells are present in the dental pulp?

Answer 18

-Mesenchymal

Question 19

In response to damage to dentin, what cells are recruited to form new odontoblast-like cells?

Answer 19

-Dental pulp progenitor cells

Question 20

What immune cells do you find in the dental pulp?

Answer 20

• Macrophages (Innate)
• Dendritic cells (Acquired)
• T and B lymphocytes

Question 21

Where does the pulp vasculature arise from?

Answer 21

-External carotid arteries from the Superior/inferior alveolar arteries

Question 22

How many arterioles do you find per root?

Answer 22

-4-8

Question 23

How do the arterioles access the root?

Answer 23

-Through the apical foramen

Question 24

T/F AS arterioles proceed into the pulp, caliber increases, and vessel wall decreases

Answer 24

True

Question 25

In the steady state of lymph flow, what is it equal to?

Answer 25

Lymph flow is equal to arterial interstitial flow

Question 26

When nerve fibers branch out through the coronal pulp what do they form?

Answer 26

-Plexus of Raschkow

Question 27

In the root pulp there are no what?

Answer 27

-Plexus of Raschkow

Question 28

What type of nerves do the incoming nerve fibers consist of?

Answer 28

- Afferent nerves from the trigeminal | - sympathetic branches from the superior cervical ganglion

Question 29

T/F The nerve bundles consist of both myelinated Ad and unmyelinated C axons

Answer 29

True

Question 30

When does myelination decrease?

Answer 30

-AS fibers proceed towards the coronal pulp

Question 31

T/F Some unmyelinated nerve axons pass into the dentinal tubules and are closely associated with odontoblasts

Answer 31

True

Question 32

What are three proposed models of dentin sensitivity?

Answer 32

- Direct innervation - Odontoblast nociception - Tubule fluid conductance

Question 33

There are nerves in some tubules goes with which proposed model of dentin sensitivity?

Answer 33

-Direct innervation

Question 34

Odontoblasts are neural crest derived, but anatomically do not synapse extensively with pulpal nerves goes with what proposed model of dentin sensitivity?

Answer 34

-Odontoblast nociception

Question 35

Local anesthetics applied to exposed dentin is ineffective, changes in fluid levels can cause sensitivity is associated with what model of dentin sensitivity?

Answer 35

-Hydrodynamic theory

Question 36

What are pulp stones?

Answer 36

-Mineralized tissue formed inappropriately in the pulp

Question 37

What is a true pulp stone?

Answer 37

-Contains tubules and they are associated with odontoblast-like cells

Question 38

What are false pulp stones?

Answer 38

-Consists of atubular mineralized tissue and sometimes with necrotic tissue at the center

Question 39

What do pulp stones often occur around?

Answer 39

-Collagen fibers

Question 40

As the tooth becomes less vital what happens to the tooth?

Answer 40

-It becomes more brittle