25. Trouble articulaire / joint disorders Flashcards

1
Q

Differentiate joint vs. soft tissue

A

Arthritis: Pain on ROM, decreased ROM, swelling, erythema

Soft tissue: ROM preserved, tendernes over bursae, tendons, or ligaments

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2
Q

general ddx 6

A

Trauma

Infection (Septic arthritis)

Crystal-induced arthritis

Osteoarthritis

Systemic disease

neoplasm

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3
Q

Hemarthrosis is associated with

A

intraarticular fractures, dislocations, ligamentous injury

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4
Q

type of septic arthitis

A

Gonoccocal

Non gonococcal

Other: Mycobacterial, fungal, Lyme

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5
Q

Gonoccocal septic arthitis triad

A

tenosynovitis, vesiculopustular skin lesions, and polyarthralgias

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6
Q

Non gonococcal bacterial infections should be suspected

A

IVDU, immunocompromised, prosthetic joint

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7
Q

Crystal-induced arthritis 2

A

Gout (monosodium urate crystal)
Pseudogout (CPPD) - calcium pyrophosphate

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8
Q

systemic artritis 9

A

Rheumatoid arthritis
Seronegative spondyloarthritis
Reactive arthritis ad max 6 weeks
Psoriatic arthritis
Inflammatory bowel disease-associated arthritis (ulcerative colitis or chron’s
Lupus
Wegener’s granulomatosis (WG)
Sarcoid periarthritis
Myelodysplastic and leukemic disorders

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9
Q

when to suspect spondyloarthritis

A

enthesitis,
dactylitis,
conjunctivitis/uveitis,
psoriasis

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10
Q

Hx red flags 6

A

Hot/swollen joints
Constitutional symptoms (high-grade fever, weight loss, malaise)
Morning stiffness >30 minutes
Night pain
Weakness
Neurological (burning pain, numbness, or paresthesia)

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11
Q

specific Extraarticular findings 3 gout/ OA/ a ankylosante/ lupus

A

Tophi (sp gout)

Skin changes:
Psoriasis,
Malar rash (butterfly rash - lupus)
Erythema nodosum - strep, sarcoidosis, TB

Eye involvement

Arthrose: Heberden (IPD) Bouchard (IPP)

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12
Q

what you are looking for a joint aspiration (4)

A

Gross appearance

Crystal analysis

White cell count and differential
<2,000/mm3 usually non-inflammatory
>20,000 suspect septic arthritis

Gram stain and Culture

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13
Q

investigations

A

CBC
LFT
ESR/CRP
ANA, RF, Anti-CCP
(HLA)-B27
Coags (in hemarthrosis)

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14
Q

monoarthropathy, rule out

A

STD - ITSS
Arthrite septique

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15
Q

ddx - referred pain

A

angina, slipped capital epiphysis presenting as knee pain, neuropathic pain

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16
Q

do not give NSAIDS to pt who have

A

renal failure

peptic ulcer disease

17
Q

general mngt of pt with MSK pain

A

demande impact sur la vie quotidienne

donne des analgesiques

ressources + canes etc

18
Q

diagnostique des lesions ligamentaires (investigation)

A

dx CLINIQUE

PAS de RX

18
Q

Définition arthrite rheumatoide 5

A

Inflammatory arthritis involving 3+ joints
Duration >6w
Positive RF and/or anti-CCP
Elevated CRP/ESR
No evidence of other diseases (eg. psoriatic arthritis, viral polyarthritis, gout/pseudogout, SLE)

19
Q

facteurs de risque RA 7

A

Age
Female
Family history
Smoking (both current and prior)
Early menarche (<10yo)
Very irregular menstrual periods
Nulliparous

20
Q

RA extra-articular findings

A

Anemia
Subcutaneous (rheumatoid) nodules
Pleuropericarditis
Neuropathy
Episcleritis/scleritis
Splenomegaly
Sjögren’s syndrome
Vasculitis
Renal disease

21
Q

what is Sjögren’s syndrome

A

immune system damages glands in your body that produce and control moisture, including in your:

Tear system.
Mouth (your salivary glands).
Nose.
Vagina.

so dry mouth, eyes, vagina, skin
epistaxis

22
Q

lupus is associated with

A

Malar/discoid rash, oral ulcers,

anti-dsDNA, anti-Sm

23
Q

Rheum arth physical exam findings - joints

A

Joint exam

Limited joint ROM

Synovial hypertrophy/thickening, effusion, inflammation, tenderness

Classically involving MCP, PIP, thumb IP, wrists, MTP (metatarsal joint pain)

24
investigations
Labs ESR, CRP RF Anti-citrullinated protein or peptide antibodies (Anti-CCP) Antinuclear antibodies (ANA) Consider CBC (anemia) , liver, kidney, uric acid, UA Imaging (joint erosions) Bilateral radiographs of hands, wrists, feet May consider MRI/ultrasound May consider arthrocentesis to rule out other causes May consider viral testing if short history and seronegative for anti-CCP and RF eg. Human parovirus B19, HBV, HCV, Lyme
25
other name for joint aspiration
arthrocentesis arthrocentèse
26
RA Treatment - medications
NSAIDs, glucocorticoids for bridging to DMARDs, flares DMARDs as soon as diagnosis of RA made (eg. within 3mo): Methotrexate is first-line (other DMARDs include sulfasalazine, leflunomide, hydroxychloroquine, biologics)
27
treatment intervention other than Rx 5
Patient education Smoking cessation Psychosocial interventions Guided exercise program PT/OT Assess CV risk factors (highest cause of mortality) (re: mainly involving pericarditis, myocarditis and heart failure, and coronary artery disease)
28
Reiter’s syndrome definition
drl articulaire + sx gyneco reactive arthritis symptoms Si sx uréthrite/cervicite (reiter – can’t see, can’t pee, can’t bend the knee)
29
Fibromylagia diagnostic criteria
dlr généralisée >3 mois deux côtés du corps (G et D) en bas et en haut points spécfiques souvent fatigue, prob de sommeil, depression/anxiety concomittant
30
tx fibromyalgie 2 non pharmaco et 5 pharmaco
exercice enseignement TCA: Amitriptyline = elavil Nortriptyline = aventyl Anticonvulsants: Gabapentin (Neurontin) pregabalin (Lyrica) ISNR = cymbalta = duloxetine