Zofran (Ondansetron) Flashcards
1
Q
Pharm and Action
A
Selective antagonist of a specific type of seratonin receptor located in the CNS at the chemoreceptor trigger zone and in the peripheral nervous system on nerve terminals of the vagus nerve; Drug blocking action may occur at both sides
2
Q
Indications
A
Nausea and Vomiting
3
Q
Contraindications
A
Hypersensitivity; Caution in patients with hepatic impairement
4
Q
Administration
A
Adult 4mg IV over 2-5 minutes; Pediatric over 40 kg 4mg, under 40 kg 0.1 mg/kg
5
Q
Side Effects and Special Notes
A
Headache, malaise, fatigue, dizziness, fever, sedation; Extrapyramidal symptoms, have Benadryl available; Pregnancy risk category B
6
Q
Class
A
A
