Oxytocin (Pitocin)

Question 1

Pharm and Action

Answer 1

Hormone which increases electrical and contractile activity in uterine smooth muscle; Can initiate or enhance rhythmic contractions of the uterus; Exhibits rapid onset with very short half-life, rapid inactivation and excretion

Question 2

Indications

Answer 2

Control of post-partum hemmorrahge

Question 3

Contraindications

Answer 3

Rule out multiple fetuses before administration

Question 4

Administration

Answer 4

10 USP units (20 mg) per ml in 1000 ml NS at flow of 10-15 drops/min titrated to effect. Rapid infusion may be indicatied

Question 5

Side effects and Special Notes

Answer 5

Administration should follow delivery of placenta; In large doses, exhibits a transient but marked vasodilation effect and reflex tachycardia; Cardiac dysrrhythmias may be precipitated or aggravated by oxytocin

Question 6

Class

Answer 6

C