Diphenhydramine (Benadryl)

Question 1

Pharm. and Actions

Answer 1

Antihistamine which blocks action of histamines released from cells during an allergic reaction; Direct CNS effects, which include stimulant or, more commonly, depressent depending on individual variation; Anticholinergic

Question 2

Indications

Answer 2

Allergic reaction; Acute dystonic reactions to antipsychotic drugs; Adjunctive therapy for anaphylaxis

Question 3

Contraindications

Answer 3

Pregnant or lactating females- relative contraindications

Question 4

Administration

Answer 4

Adult 25-50 mg slow IV push; Peds 1-2 mg/kg slow IV or IO push

Question 5

Side effects and special notes

Answer 5

Sedation, blurred vision, anticholinergic effects; May enhance effects of alcohol and other depressants; is not the first line drug for allergic reactions

Question 6

Class

Answer 6

A