Glucagon

Question 1

Pharm. and Action

Answer 1

Increases blood glucose concentration by converting liver glycogen into glucose; Parenteral administration of glucagon produces relaxation of the smooth muscle of the stomach, duodenum, small bowel, and colon

Question 2

Indications

Answer 2

Hypoglycemia when IV access is unavailable or delayed

Question 3

Contraindications

Answer 3

None

Question 4

Administration

Answer 4

Dissolve the lyophylized glucagon in accompanying solvent; Give 1 unit (1 mg) of glucagon IM; if no effect wait 8-10 min., repeat 1 unit (1 mg); IV glucose must be given if patient fails to respond to glucagon

Question 5

Side Effects and Special Notes

Answer 5

N/V and generalized allergic reactions have been reported; Glucagon should not be used in concentrations greater than 1 unit (1 mg); should not be used unless solution is clear and of water-like consistency

Question 6

Class

Answer 6

A